Comparative study of the clinical characteristics and epidemiological trend of 244 COVID-19 infected children with or without GI symptoms
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SciScore for 10.1101/2020.04.29.20084244: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: Study design and patients: This was a retrospective single-center study approved by the Research Ethics Board of Wuhan Children’s Hospital (WHCH2020022). Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources The data was analyzed by SPSS 26.0, and P<0.05 was used to determine significance. SPSSsuggested: (SPSS, RRID:SCR_002865)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the …SciScore for 10.1101/2020.04.29.20084244: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: Study design and patients: This was a retrospective single-center study approved by the Research Ethics Board of Wuhan Children’s Hospital (WHCH2020022). Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources The data was analyzed by SPSS 26.0, and P<0.05 was used to determine significance. SPSSsuggested: (SPSS, RRID:SCR_002865)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:There are limitations of this study. This is a retrospective cohort study so we may not be able to establish any causal relationship. The sample size of patients with GI symptoms is relatively small, due to its low incidence so we may miss out some risk factors for its occurrence. The laboratory examinations and fecal SARS-CoV-2 RNA detection were not done in all patients and this may generate bias in the data analysis. Our study is one of the largest of its kind, and we showed the differences between clinical and laboratory characteristics of patients with or without GI symptoms, which were different from adults. Both pediatricians and patients need to pay more attention to COVID-19 children with GI symptoms even though they have mild symptoms and stable vital signs. An upward trend in asymptomatic infections also means the public should be on guard at all times.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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