1. SciScore for 10.1101/2022.01.13.22269257: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    No key resources detected.

    Results from OddPub: Thank you for sharing your code and data.

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    There are a number of limitations to these data and analyses. First, Ct values report viral RNA copies and do not necessarily capture infectiousness. While we chose a Ct value cutoff of 30 as a proxy for infectiousness13–17, this threshold should not be considered a perfect predictor of infectiousness. Second, the Ct values reported here are from samples that each combined anterior nares and oropharyngeal swabs and were performed on the Roche Cobas platform; results may differ by anatomical site and by PCR platform24–27. Third, this relatively small sample set was obtained in a population that is not representative of the general population. The study population of working individuals is younger and generally healthier, with high vaccination coverage, than to the general population, thus infections in this group may have a shorter clearance phase on average than in the general population. Furthermore, this cohort is under intensive testing, behavior protocols, and case-finding efforts; individuals detected due to symptom onset or concern for contacts may be detected earlier in infection than would be typical in the community. While results from a Japanese study suggest similar viral kinetics in a distinct population21, additional analyses from larger cohorts and across additional demographic groups are urgently needed. Finally, not all infected individuals were serially tested until obtaining a negative test result. As some of the trajectories reported here are right censored...

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

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