Profiling Cases With Nonrespiratory Symptoms and Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infections in Mexico City

  1. Omar Yaxmehen Bello-Chavolla
  2. Neftali Eduardo Antonio-Villa
  3. Arsenio Vargas-Vázquez
  4. Carlos A Fermín-Martínez
  5. Alejandro Márquez-Salinas
  6. Jessica Paola Bahena-López

Reviewed by

Read the full article

Listed in

Log in to save this article

Abstract

We profiled cases with nonrespiratory symptoms (NRS) and asymptomatic severe acute respiratory syndrome coronavirus 2 infections assessed within Mexico City’s Epidemiological Surveillance System. Initially asymptomatic or NRS cases have decreased risk of adverse outcomes compared with cases with respiratory symptoms. Comorbidity and age influence symptom development in initially asymptomatic cases.

Article activity feed

  1. Version published to 10.1093/cid/ciaa1288
  2. Version published to 10.1101/2020.07.02.20145516v3 on medRxiv
  3. Version published to 10.1101/2020.07.02.20145516v2 on medRxiv
  4. ScreenIT

    SciScore for 10.1101/2020.07.02.20145516: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board Statementnot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    No key resources detected.

    Results from OddPub: Thank you for sharing your code and data.

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Additional limitations include nonassessment of atypical SARS-CoV-2 symptoms which might occur amongst otherwise asymptomatic cases, particularly in older adults, and the lack of systematized sampling, which does not allow for an accurate estimation for the rates of asymptomatic cases in Mexico City. Our results highlight the need to systematize definitions of asymptomatic cases and extend testing by contact tracing to detect asymptomatic SARS-CoV-2 infections as one of the mitigations strategies to reduce transmission of SARS-CoV-2 in Mexico City and Mexico in general.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  5. Version published to 10.1101/2020.07.02.20145516v1 on medRxiv