Changing Dynamics of COVID-19 Deaths During the SARS-CoV2 B.1.617.2 (Delta Variant) Outbreak in England and Wales: Reduced COVID-19 Deaths Among the Care Home Residents

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Abstract

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  1. SciScore for 10.1101/2022.03.05.22271084: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Ethicsnot detected.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Limitations of our study is, it is an observational study of publicly reported data. However, this database of outcomes among the confirmed 593,572 Delta variant cases in UK technical briefings (as shown in Table 4, for period ending September 12, 2021, week 36), is correlating well with our comprehensive analysis of all the SARS-CoV2 weekly case rates, hospitalizations and deaths during the Delta variant surge in UK for the same period ending week 36 in 2021 (Figures 1-4). The other limitations of our study are the generalizability of the findings is limited to UK population.

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.


    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  2. SciScore for 10.1101/2022.02.09.22270705: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Ethicsnot detected.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Limitations of our study is that it is an observational study of publicly reported data of the deaths from all causes and COVID-19 in England and Wales during the SARS-CoV2 pandemic and do not involve review of the individual charts to accurately adjudicate the deaths. The other limitations of our study are the generalizability of the findings is limited to the England and Wales population. Despite the declining COVID-19 deaths observed during the Delta variant surge in our study, the percent of deaths in Care Homes due to COVID-19 during the Delta variant surge is 2.5% which is higher than deaths due COVID-19 at Homes (1.6%). As per the data of 2002, about 0.7% of England and Wales population (n=442,888) living in the Care Homes are at increased risk for mortality as was observed during the first two waves with COVID-19 infections, due to advanced age of the Care Home population (75.6% and 50.3% of Care Home residents are ≥75 years and ≥85 years age groups respectively in England and Wales) and multiple preexisting conditions among the Care Home population19,30.

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a protocol registration statement.

    Results from scite Reference Check: We found no unreliable references.


    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.