Unveiling distinct neuroimmune responses in mouse models of cervical spinal cord injury: Hemisection versus hemicontusion

  1. Wei Chen
  2. Lucille Adam
  3. Pauline Michel-Flutot
  4. Arnaud Mansart
  5. Stéphane Vinit
  6. Isabelle Vivodtzev

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Abstract

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  1. Version published to 10.1016/j.expneurol.2026.115661
  2. Arcadia Science

    two cervical spinal cord injury (SCI) models: C2 hemisection (C2HS) and C3 hemicontusion (C3HC)

    Perhaps this comparison has already been done, but did you consider also including a control group of mice that received a superficial surgery (skin and muscles retracted) but no cervical spinal cord injury? I'd be curious whether/how much the localized tissue inflammation had downstream effects on the cervial spinal cord.

  3. Version published to 10.1101/2025.08.02.668124 on bioRxiv