Upper respiratory tract SARS-CoV-2 RNA loads in symptomatic and asymptomatic children and adults
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SciScore for 10.1101/2021.03.03.21252814: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: The current study was approved by the Research Ethics Committee of Hospital Clínico Universitario INCLIVA (March 2020) Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources The analyses were performed using SPSS version 20.0 (SPSS, Chicago, IL, USA). SPSSsuggested: (SPSS, RRID:SCR_002865)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations …SciScore for 10.1101/2021.03.03.21252814: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: The current study was approved by the Research Ethics Committee of Hospital Clínico Universitario INCLIVA (March 2020) Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources The analyses were performed using SPSS version 20.0 (SPSS, Chicago, IL, USA). SPSSsuggested: (SPSS, RRID:SCR_002865)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:The current study has several limitations. First, clinical outcome of asymptomatic individuals, which may be determined by peak viral load, could not be ascertained in a large number of participants. Second, only initial SARS-CoV-2 loads were taken into consideration in the analyses, so that we could not have captured the true virus replication rate on an individual basis. Third, no attempt was made to subcategorize individuals according to their baseline medical condition. In summary, we conclude that SARS-CoV-2 RNA loads in non-hospitalized or asymptomatic COVID-19 children of all ages were comparable to those estimated in adults. Our findings indicate that children may spread SARS-CoV-2 in the general population at the same level as adults.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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