Evaluated articles

Quantitative mapping of human hair greying and reversal in relation to life stress

1. Ayelet M Rosenberg
2. Shannon Rausser
3. Junting Ren
4. Eugene V Mosharov
5. Gabriel Sturm
6. R Todd Ogden
7. Purvi Patel
8. Rajesh Kumar Soni
9. Clay Lacefield
10. Desmond J Tobin
11. Ralf Paus
12. Martin Picard

• Curated by eLife

  Evaluation Summary:

  This is an interesting and informative study reporting on the molecular features of reversible hair graying in humans and the connection with psychological stress. The study appears to have been very well conducted and the interpretations are generally supported by the data. While the results are primarily correlative at this stage, this work will set the stage for future more mechanistic studies and represents an important conceptual and methodological advance.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #2 agreed to share their names with the authors.)

Reviewed by eLife, preLights

Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses

1. Shengsheng Lu
2. Xiaoyan Pan
3. Daiwei Chen
4. Xi Xie
5. Yan Wu
6. Weijuan Shang
7. Xiaming Jiang
8. Yuan Sun
9. Sheng Fan
10. Jian He

Reviewed by preLights

Development of the foregut in Katharina tunicata (Mollusca; Polyplacophora)

1. Brandy S. Biggar

Reviewed by preLights

Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression

1. Alexandra Despang
2. Robert Schöpflin
3. Martin Franke
4. Salaheddine Ali
5. Ivana Jerkovic
6. Christina Paliou
7. Wing-Lee Chan
8. Bernd Timmermann
9. Lars Wittler
10. Martin Vingron
11. Stefan Mundlos
12. Daniel M. Ibrahim

Reviewed by preLights

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

1. Anne Ramsay Bowden
2. David A Morales-Juarez
3. Matylda Sczaniecka-Clift
4. Maria Martin Agudo
5. Natalia Lukashchuk
6. John Christopher Thomas
7. Stephen P Jackson

Reviewed by preLights

A ciliopathy complex builds distal appendages to initiate ciliogenesis

1. Dhivya Kumar
2. Addison Rains
3. Vicente Herranz-Pérez
4. Quanlong Lu
5. Xiaoyu Shi
6. Danielle L. Swaney
7. Erica Stevenson
8. Nevan J. Krogan
9. Bo Huang
10. Christopher Westlake
11. Jose Manuel Garcia-Verdugo
12. Bradley K. Yoder
13. Jeremy F. Reiter

Reviewed by preLights

Negative frequency‐dependent selection maintains coexisting genotypes during fluctuating selection

1. Caroline B. Turner
2. Sean W. Buskirk
3. Katrina B. Harris
4. Vaughn S. Cooper

Reviewed by preLights

Super‐beacons: Open‐source probes with spontaneous tuneable blinking compatible with live‐cell super‐resolution microscopy

1. Pedro M. Pereira
2. Nils Gustafsson
3. Mark Marsh
4. Musa M. Mhlanga
5. Ricardo Henriques

Reviewed by preLights

Transcription shapes genome-wide histone acetylation patterns

1. Benjamin J. E. Martin
2. Julie Brind’Amour
3. Anastasia Kuzmin
4. Kristoffer N. Jensen
5. Zhen Cheng Liu
6. Matthew Lorincz
7. LeAnn J. Howe

Reviewed by preLights

Accurate detection of m6A RNA modifications in native RNA sequences

1. Huanle Liu
2. Oguzhan Begik
3. Morghan C. Lucas
4. Jose Miguel Ramirez
5. Christopher E. Mason
6. David Wiener
7. Schraga Schwartz
8. John S. Mattick
9. Martin A. Smith
10. Eva Maria Novoa

Reviewed by preLights

Passage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes

1. A Gastaldello
2. SH Ramarathinam
3. A Bailey
4. R Owen
5. S Turner
6. A Kontouli
7. T Elliott
8. P Skipp
9. AW Purcell
10. HV Siddle

Reviewed by preLights

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

1. Candice R. Gurbatri
2. Ioana Lia
3. Rosa Vincent
4. Courtney Coker
5. Samuel Castro
6. Piper M. Treuting
7. Taylor E. Hinchliffe
8. Nicholas Arpaia
9. Tal Danino

Reviewed by preLights

Apical Constriction Reversal upon Mitotic Entry Underlies Different Morphogenetic Outcomes of Cell Division

1. Clint S. Ko
2. Prateek Kalakuntla
3. Adam C. Martin

Reviewed by preLights

Human DNA-PK activates a STING-independent DNA sensing pathway

1. Katelyn Burleigh
2. Joanna H. Maltbaek
3. Stephanie Cambier
4. Richard Green
5. Michael Gale
6. Richard C. James
7. Daniel B. Stetson

Reviewed by preLights

Early-Life Social Experience Shapes Social Avoidance Reactions in Larval Zebrafish

1. Antonia H. Groneberg
2. João C. Marques
3. A. Lucas Martins
4. Ruth Diez del Corral
5. Gonzalo G. de Polavieja
6. Michael B. Orger

Reviewed by preLights

Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability

1. Sheldon Decombe
2. François Loll
3. Laura Caccianini
4. Kévin Affannoukoué
5. Ignacio Izeddin
6. Julien Mozziconacci
7. Christophe Escudé
8. Judith Lopes

Reviewed by preLights

Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles

1. Jia Hui Li
2. Paula Santos-Otte
3. Braedyn Au
4. Jakob Rentsch
5. Stephan Block
6. Helge Ewers

Reviewed by preLights

Characterization of the novel mitochondrial genome segregation factor TAP110 in Trypanosoma brucei

1. Simona Amodeo
2. Ana Kalichava
3. Albert Fradera-Sola
4. Eloïse Bertiaux-Lequoy
5. Paul Guichard
6. Falk Butter
7. Torsten Ochsenreiter

Reviewed by preLights

Subthreshold Voltage Analysis Demonstrates Neuronal Cell-Surface Sialic Acids Modulate Excitability and Network Integration

1. Rishikesh U. Kulkarni
2. Catherine L. Wang
3. Carolyn R. Bertozzi

Reviewed by preLights

Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network

1. Joshua Hutchings
2. Viktoriya G. Stancheva
3. Nick R. Brown
4. Alan C. M. Cheung
5. Elizabeth A. Miller
6. Giulia Zanetti

Reviewed by eLife, preLights