Showing page 44 of 72 pages of list content

  1. Chemogenetics defines a short-chain fatty acid receptor gut–brain axis

    This article has 12 authors:
    1. Natasja Barki
    2. Daniele Bolognini
    3. Ulf Börjesson
    4. Laura Jenkins
    5. John Riddell
    6. David I Hughes
    7. Trond Ulven
    8. Brian D Hudson
    9. Elisabeth Rexen Ulven
    10. Niek Dekker
    11. Andrew B Tobin
    12. Graeme Milligan
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      In this paper the authors study the Rolle of small chain fatty acids receptors FFA2 and FFA3 in the dorsal root ganglia with the goal to define molecularly a gut to brain axis. They identified MOMBA as a compound that binds to FFA2. This paper presents a powerful screening strategy to identify receptor agonists. The main concerns are the specificity of the model, and the functional purpose of this gut to brain axis.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife, preLights

    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity
  2. Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease

    This article has 30 authors:
    1. Constanze Depp
    2. Ting Sun
    3. Andrew Octavian Sasmita
    4. Lena Spieth
    5. Stefan A. Berghoff
    6. Taisiia Nazarenko
    7. Katharina Overhoff
    8. Agnes A. Steixner-Kumar
    9. Swati Subramanian
    10. Sahab Arinrad
    11. Torben Ruhwedel
    12. Wiebke Möbius
    13. Sandra Göbbels
    14. Gesine Saher
    15. Hauke B. Werner
    16. Alkmini Damkou
    17. Silvia Zampar
    18. Oliver Wirths
    19. Maik Thalmann
    20. Mikael Simons
    21. Takashi Saito
    22. Takaomi Saido
    23. Dilja Krueger-Burg
    24. Riki Kawaguchi
    25. Michael Willem
    26. Christian Haass
    27. Daniel Geschwind
    28. Hannelore Ehrenreich
    29. Ruth Stassart
    30. Klaus-Armin Nave

    Reviewed by preLights

    This article has 1 evaluationAppears in 2 listsLatest version Latest activity
  3. A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

    This article has 22 authors:
    1. Michael Alexanian
    2. Pawel F. Przytycki
    3. Rudi Micheletti
    4. Arun Padmanabhan
    5. Lin Ye
    6. Joshua G. Travers
    7. Barbara Gonzalez Teran
    8. Qiming Duan
    9. Sanjeev S. Ranade
    10. Franco Felix
    11. Ricardo Linares-Saldana
    12. Yu Huang
    13. Gaia Andreoletti
    14. Jin Yang
    15. Kathryn N. Ivey
    16. Rajan Jain
    17. Timothy A. McKinsey
    18. Michael G. Rosenfeld
    19. Casey Gifford
    20. Katherine S. Pollard
    21. Saptarsi M. Haldar
    22. Deepak Srivastava

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  4. A unified platform to manage, share, and archive morphological and functional data in insect neuroscience

    This article has 13 authors:
    1. Stanley Heinze
    2. Basil el Jundi
    3. Bente G Berg
    4. Uwe Homberg
    5. Randolf Menzel
    6. Keram Pfeiffer
    7. Ronja Hensgen
    8. Frederick Zittrell
    9. Marie Dacke
    10. Eric Warrant
    11. Gerit Pfuhl
    12. Jürgen Rybak
    13. Kevin Tedore
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      This manuscript will be of interest to insect neuroscientists and broadly to the neuroanatomy community. It presents a new web resource that collects and displays neuron, brain region and species data in user-friendly ways. If taken up by the community, it has the potential to become an important data hub.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

    Reviewed by eLife, preLights

    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity