Evaluated articles

A list by preLights

Articles that have been evaluated by preLights.

1271 articlesLast updated

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  7. Cholesterol and matrisome pathways dysregulated in human APOE ε4 glia

    1. Julia TCW
    2. Shuang A. Liang
    3. Lu Qian
    4. Nina H Pipalia
    5. Michael J. Chao
    6. Yang Shi
    7. Sarah E. Bertelsen
    8. Manav Kapoor
    9. Edoardo Marcora
    10. Elizabeth Sikora
    11. David M. Holtzman
    12. Frederick R. Maxfield
    13. Bin Zhang
    14. Minghui Wang
    15. Wayne W. Poon
    16. Alison M. Goate

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Unexpected plasticity in the life cycle of Trypanosoma brucei

    1. Sarah Schuster
    2. Jaime Lisack
    3. Ines Subota
    4. Henriette Zimmermann
    5. Christian Reuter
    6. Tobias Mueller
    7. Brooke Morriswood
    8. Markus Engstler

    • Curated by eLife

      Evaluation Summary:

      This paper describes the transmission of Trypanosoma brucei by the Tsetse vector. As part of these studies, the authors discovered that (i) a single parasite is sufficient for transmission and (ii) two stages of the Trypanosoma brucei life cycle (slender and stumpy forms) can be transmitted by the Tsetse vector - although the stumpy form developed more rapidly into proliferative parasites in the Tsetse midgut. The results are unexpected because it was previously thought that only stumpy forms were important for transmission.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #3 agreed to share their name with the authors.)

    Reviewed by eLife, preLights

    6 evaluationsAppears in 2 listsLatest version Latest activity

  14. A functional genetic toolbox for human tissue-derived organoids

    1. Dawei Sun
    2. Lewis Evans
    3. Francesca Perrone
    4. Vanesa Sokleva
    5. Kyungtae Lim
    6. Saba Rezakhani
    7. Matthias Lutolf
    8. Matthias Zilbauer
    9. Emma L Rawlins

    • Curated by eLife

      Evaluation Summary:

      In this paper Sun and colleagues aimed to demonstrate the feasibility of using CRISPR-based gene editing techniques applied to tissue-derived human fetal lung organoids. While previous studies have used CRISPR-Cas9 to perform knock-in or knock-out studies in organoids (such as intestinal, hepatic or tumor organoids), this is the first report to apply these tools to a tissue-derived lung organoid model. A major strength of this report is the additional use of CRISPRi and CRISPRa technologies. The work is well done, clearly presented and makes an important contribution to the literature.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #3 agreed to share their name with the authors.)

    Reviewed by eLife, preLights

    6 evaluationsAppears in 2 listsLatest version Latest activity

  15. Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains

    1. Xiaoyu Sun
    2. Donovan Y.Z. Phua
    3. Lucas Axiotakis
    4. Mark A. Smith
    5. Elizabeth Blankman
    6. Rui Gong
    7. Robert C. Cail
    8. Santiago Espinosa de los Reyes
    9. Mary C. Beckerle
    10. Clare M. Waterman
    11. Gregory M. Alushin

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  20. Cytostatic hypothermia and its impact on glioblastoma and survival

    1. Syed Faaiz Enam
    2. Cem Y. Kilic
    3. Jianxi Huang
    4. Brian J. Kang
    5. Reed Chen
    6. Connor S. Tribble
    7. Ekaterina Ilich
    8. Martha I. Betancur
    9. Stephanie J. Blocker
    10. Steven J. Owen
    11. Anne F. Buckley
    12. Johnathan G. Lyon
    13. Ravi V. Bellamkonda

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity
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