Evaluated articles

High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity

1. Kaia Mattioli
2. Pieter-Jan Volders
3. Chiara Gerhardinger
4. James C. Lee
5. Philipp G. Maass
6. Marta Melé
7. John L. Rinn

Reviewed by preLights

Direct ETTIN-auxin interaction controls chromatin states in gynoecium development

1. André Kuhn
2. Sigurd Ramans Harborough
3. Heather M McLaughlin
4. Bhavani Natarajan
5. Inge Verstraeten
6. Jiří Friml
7. Stefan Kepinski
8. Lars Østergaard

Reviewed by preLights

Mechanisms underlying the cooperation between loss of epithelial polarity and Notch signaling during neoplastic growth in Drosophila

1. Rémi Logeay
2. Charles Géminard
3. Patrice Lassus
4. Miriam Rodríguez-Vázquez
5. Diala Kantar
6. Lisa Heron-Milhavet
7. Bettina Fischer
8. Sarah J. Bray
9. Jacques Colinge
10. Alexandre Djiane

Reviewed by preLights

Visualizing cellular and tissue ultrastructure using Ten-fold Robust Expansion Microscopy (TREx)

1. Hugo GJ Damstra
2. Boaz Mohar
3. Mark Eddison
4. Anna Akhmanova
5. Lukas C Kapitein
6. Paul W Tillberg

• Curated by eLife

  Evaluation Summary:

  This manuscript reports a robust and well-characterized expansion method that achieves 10X expansion with a single expansion step using a simple, easy-to-use protocol. The new protocol leads to an enabling methodology for super-resolution imaging of various sub-cellular structures and organelles and is likely to have a high impact.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

Reviewed by eLife, preLights

Precise genomic deletions using paired prime editing

1. Junhong Choi
2. Wei Chen
3. Chase C. Suiter
4. Choli Lee
5. Florence M. Chardon
6. Wei Yang
7. Anh Leith
8. Riza M. Daza
9. Beth Martin
10. Jay Shendure

Reviewed by preLights

Emergent RNA–RNA interactions can promote stability in a facultative phototrophic endosymbiosis

1. Benjamin H. Jenkins
2. Finlay Maguire
3. Guy Leonard
4. Joshua D. Eaton
5. Steven West
6. Benjamin E. Housden
7. David S. Milner
8. Thomas A. Richards

Reviewed by preLights

Systematic reconstruction of the cellular trajectories of mammalian embryogenesis

1. Chengxiang Qiu
2. Junyue Cao
3. Tony Li
4. Sanjay Srivatsan
5. Xingfan Huang
6. Diego Calderon
7. William Stafford Noble
8. Christine M. Disteche
9. Malte Spielmann
10. Cecilia B. Moens
11. Cole Trapnell
12. Jay Shendure

Reviewed by preLights

Spatial heterogeneity of cell-matrix adhesive forces predicts human glioblastoma migration

1. Rasha Rezk
2. Bill Zong Jia
3. Astrid Wendler
4. Ivan Dimov
5. Colin Watts
6. Athina E Markaki
7. Kristian Franze
8. Alexandre J Kabla

Reviewed by preLights

Depression of heart rate in fish at critically high temperatures is due to atrioventricular block

1. Jaakko Haverinen
2. Matti Vornanen

Reviewed by preLights

The nucleocytosolic O-fucosyltransferase SPINDLY affects protein expression and virulence in Toxoplasma gondii

1. Giulia Bandini
2. Carolina Agop-Nersesian
3. Hanke van der Wel
4. Msano Mandalasi
5. Hyun W. Kim
6. Christopher M. West
7. John Samuelson

Reviewed by preLights

Gender Imbalance in the Editorial Activities of a Researcher-led Journal

1. Tal Seidel Malkinson
2. Devin B. Terhune
3. Mathew Kollamkulam
4. Maria J. Guerreiro
5. Dani S. Bassett
6. Tamar R. Makin

Reviewed by preLights

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

1. David H. Brann
2. Tatsuya Tsukahara
3. Caleb Weinreb
4. Marcela Lipovsek
5. Koen Van den Berge
6. Boying Gong
7. Rebecca Chance
8. Iain C. Macaulay
9. Hsin-Jung Chou
10. Russell B. Fletcher
11. Diya Das
12. Kelly Street
13. Hector Roux de Bezieux
14. Yoon-Gi Choi
15. Davide Risso
16. Sandrine Dudoit
17. Elizabeth Purdom
18. Jonathan Mill
19. Ralph Abi Hachem
20. Hiroaki Matsunami
21. Darren W. Logan
22. Bradley J. Goldstein
23. Matthew S. Grubb
24. John Ngai
25. Sandeep Robert Datta

Reviewed by ScreenIT, preLights

Circularly permuted LOV domain as an engineering module for optogenetic tools

1. Lequn Geng
2. Jiaqi Shen
3. Wenjing Wang

Reviewed by preLights

Transcriptome analysis of developmental stages of cocoa pod borer, Conopomorpha cramerella : A polyphagous insect pest of economic importance in Southeast Asia

1. Chia Lock Tan
2. Rosmin Kasran
3. Wei Wei Lee
4. Wai Mun Leong

Reviewed by preLights

Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism

1. Joanna Szczepaniak
2. Peter Holmes
3. Karthik Rajasekar
4. Renata Kaminska
5. Firdaus Samsudin
6. Patrick George Inns
7. Patrice Rassam
8. Syma Khalid
9. Seán M. Murray
10. Christina Redfield
11. Colin Kleanthous

Reviewed by preLights

Pulmonary natural killer cells control neutrophil intravascular motility and response to acute inflammation

1. J. Secklehner
2. K. De Filippo
3. J. B. G. Mackey
4. J. Vuononvirta
5. X. L. Raffo Iraolagoitia
6. A. J. McFarlane
7. M. Neilson
8. M. B. Headley
9. M. F. Krummel
10. N. Guerra
11. L. M. Carlin

Reviewed by preLights

EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break

1. Teressa Paulsen
2. Pumoli Malapati
3. Rebeka Eki
4. Tarek Abbas
5. Anindya Dutta

Reviewed by preLights

Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics

1. Hamish W. King
2. Nara Orban
3. John C. Riches
4. Andrew J. Clear
5. Gary Warnes
6. Sarah A. Teichmann
7. Louisa K. James

Reviewed by preLights

Two redundant ubiquitin‐dependent pathways of BRCA1 localization to DNA damage sites

1. Alana Sherker
2. Natasha Chaudhary
3. Salomé Adam
4. Anne Margriet Heijink
5. Sylvie M Noordermeer
6. Amélie Fradet‐Turcotte
7. Daniel Durocher

Reviewed by preLights

The autophagic membrane tether ATG2A transfers lipids between membranes

1. Shintaro Maeda
2. Chinatsu Otomo
3. Takanori Otomo

Reviewed by preLights