Evaluated articles

Mechanical stretch regulates macropinocytosis in Hydra vulgaris

1. Taylor D. Skokan
2. Bert Hobmayer
3. Kara L. McKinley
4. Ronald D. Vale

Reviewed by Review Commons, preLights

Single mutation makes Escherichia coli an insect mutualist

1. Ryuichi Koga
2. Minoru Moriyama
3. Naoko Onodera-Tanifuji
4. Yoshiko Ishii
5. Hiroki Takai
6. Masaki Mizutani
7. Kohei Oguchi
8. Reiko Okura
9. Shingo Suzuki
10. Yasuhiro Gotoh
11. Tetsuya Hayashi
12. Masahide Seki
13. Yutaka Suzuki
14. Yudai Nishide
15. Takahiro Hosokawa
16. Yuichi Wakamoto
17. Chikara Furusawa
18. Takema Fukatsu

Reviewed by preLights

ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations

1. Coline Arnould
2. Vincent Rocher
3. Aldo S. Bader
4. Emma Lesage
5. Nadine Puget
6. Thomas Clouaire
7. Raphael Mourad
8. Daan Noordermeer
9. Martin Bushell
10. Gaëlle Legube

Reviewed by preLights

The roles of distinct Ca ²⁺ signaling mediated by Piezo and inositol triphosphate receptor (IP3R) in the remodeling of E-cadherin during cell dissemination

1. Alejandra J.H. Cabrera
2. Barry M. Gumbiner
3. Young V. Kwon

Reviewed by Review Commons, preLights

An effective workshop on “How to be an Effective Mentor for Underrepresented STEM Trainees”

1. Andrea G Marshall
2. Zer Vue
3. Caroline B Palavicino-Maggio
4. Kit Neikirk
5. Heather K Beasley
6. Edgar Garza-Lopez
7. Sandra A Murray
8. Denise Martinez
9. Amber Crabtree
10. Zachary C Conley
11. Larry Vang
12. Jamaine S Davis
13. Keesha L Powell-Roach
14. Susan Campbell
15. Lillian J Brady
16. Angyth B Dal
17. Bryanna Shao
18. Stefanie Alexander
19. Nancy Vang
20. Neng Vue
21. Mein Vue
22. Haysetta D Shuler
23. Elsie C Spencer
24. Derrick J Morton
25. Antentor Hinton

Reviewed by preLights

Oxycodone decreases anxiety-like behavior in the elevated plus-maze test in male and female rats

1. Adriaan W. Bruijnzeel
2. Azin Behnood-Rod
3. Wendi Malphurs
4. Ranjithkumar Chellian
5. Robert M. Caudle
6. Marcelo Febo
7. Barry Setlow
8. John K. Neubert

Reviewed by preLights

Yersinia pestis genomes reveal plague in Britain 4,000 years ago

1. Pooja Swali
2. Rick Schulting
3. Alexandre Gilardet
4. Monica Kelly
5. Kyriaki Anastasiadou
6. Isabelle Glocke
7. Tony Audsley
8. Louise Loe
9. Teresa Fernández-Crespo
10. Javier Ordoño
11. David Walker
12. Tom Davy
13. Marina Silva
14. Mateja Hajdinjak
15. Anders Bergström
16. Thomas Booth
17. Pontus Skoglund

Reviewed by preLights

cGAS recruitment to micronuclei is dictated by pre-existing nuclear chromatin status

1. Kate M. MacDonald
2. Shirony Nicholson-Puthenveedu
3. Maha M. Tageldein
4. Cheryl Arrowsmith
5. Shane M. Harding

Reviewed by preLights

Microstructured Hydrogels to Guide Self‐Assembly and Function of Lung Alveolospheres

1. Claudia Loebel
2. Aaron I. Weiner
3. Madeline K. Eiken
4. Jeremy B. Katzen
5. Michael P. Morley
6. Vikram Bala
7. Fabian L. Cardenas‐Diaz
8. Matthew D. Davidson
9. Kazushige Shiraishi
10. Maria C. Basil
11. Laura T. Ferguson
12. Jason R. Spence
13. Matthias Ochs
14. Michael F. Beers
15. Edward E. Morrisey
16. Andrew E. Vaughan
17. Jason A. Burdick

Reviewed by preLights

Species-specific mitochondria dynamics and metabolism regulate the timing of neuronal development

1. Ryohei Iwata
2. Pierre Casimir
3. Emir Erkol
4. Leïla Boubakar
5. Mélanie Planque
6. Martyna Ditkowska
7. Katlijn Vints
8. Suresh Poovathingal
9. Vaiva Gaspariunaite
10. Matthew Bird
11. Nikky Corthout
12. Pieter Vermeersch
13. Kristofer Davie
14. Natalia V. Gounko
15. Stein Aerts
16. Bart Ghesquière
17. Sarah-Maria Fendt
18. Pierre Vanderhaeghen

Reviewed by preLights

Bacterial filamentation as a mechanism for cell-to-cell spread within an animal host

1. Tuan D. Tran
2. Munira Aman Ali
3. Davin Lee
4. Marie-Anne Félix
5. Robert J. Luallen

Reviewed by preLights

A persistent behavioral state enables sustained predation of humans by mosquitoes

1. Trevor R Sorrells
2. Anjali Pandey
3. Adriana Rosas-Villegas
4. Leslie B Vosshall

• Curated by eLife

  Evaluation Summary:

  This manuscript describes a female mosquito's behavior after a brief exposure to CO2, which has long been known to trigger host-seeking behaviour in female mosquitoes. The authors develop optogenetic tools in Aedes aegypti that enable the controlled delivery of 'fictive' CO2 to them. They show that a brief pulse of fictive CO2 alters the behavioral state of female mosquitoes, which lasts about 15 minutes. It provides new insights into how activation of CO2-sensing olfactory neurons alters the behavioral state of a mosquito towards sensory cues to increase host-seeking behaviors. The study will be of great value to the vector biology community, as well as to neurobiologists in general.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #2 agreed to share their name with the authors.)

Reviewed by eLife, preLights

Differential mosquito attraction to humans is associated with skin-derived carboxylic acid levels

1. Maria Elena De Obaldia
2. Takeshi Morita
3. Laura C. Dedmon
4. Daniel J. Boehmler
5. Caroline S. Jiang
6. Emely V. Zeledon
7. Justin R. Cross
8. Leslie B. Vosshall

Reviewed by preLights

Isolation disrupts social interactions and destabilizes brain development in bumblebees

1. Z. Yan Wang
2. Grace C. McKenzie-Smith
3. Weijie Liu
4. Hyo Jin Cho
5. Talmo Pereira
6. Zahra Dhanerawala
7. Joshua W. Shaevitz
8. Sarah D. Kocher

Reviewed by preLights

Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

1. Mírian Romitti
2. Adrien Tourneur
3. Barbara de Faria da Fonseca
4. Gilles Doumont
5. Pierre Gillotay
6. Xiao-Hui Liao
7. Sema Elif Eski
8. Gaetan Van Simaeys
9. Laura Chomette
10. Helene Lasolle
11. Olivier Monestier
12. Dominika Figini Kasprzyk
13. Vincent Detours
14. Sumeet Pal Singh
15. Serge Goldman
16. Samuel Refetoff
17. Sabine Costagliola

Reviewed by preLights

Angiocrine IGFBP3 Spatially Coordinates IGF Signaling During Neonatal Cardiac Regeneration

1. Shah R. Ali
2. Waleed Elhelaly
3. Ngoc Uyen Nhi Nguyen
4. Shujuan Li
5. Ivan Menendez-Montes
6. Zhaoning Wang
7. Miao Cui
8. Abdallah Elnwasany
9. Feng Xiao
10. Suwannee Thet
11. Nicholas T. Lam
12. Alisson Cardoso
13. Ana Helena Pereira
14. Mohammad Goodarzi
15. Michael T. Kinter
16. Andrew Lemoff
17. Luke I. Szweda
18. John Shelton
19. Wataru Kimura
20. Hesham A. Sadek

Reviewed by preLights

Using Polyacrylamide Hydrogels to Model Physiological Aortic Stiffness Reveals that Microtubules Are Critical Regulators of Isolated Smooth Muscle Cell Morphology and Contractility

1. Sultan Ahmed
2. Robert. T. Johnson
3. Reesha Solanki
4. Teclino Afewerki
5. Finn Wostear
6. Derek. T. Warren

Reviewed by preLights

Analysis of science journalism reveals gender and regional disparities in coverage

1. Natalie R Davidson
2. Casey S Greene

• Curated by eLife

  eLife assessment

  This important bibliometric analysis shows that authors of scientific papers whose names suggest they are female or East Asian get quoted less often in news stories about their work. While caveats are inevitable in this type of study, the evidence for the authors' claims is convincing, with a rigorous, and importantly, reproducible analysis of over 20,000 articles from across 15 years. This paper will be of interest to science journalists and to researchers who study science communication.

Reviewed by eLife, preLights

Reprogramming the topology of the nociceptive circuit in C. elegans reshapes sexual behavior

1. Vladyslava Pechuk
2. Gal Goldman
3. Yehuda Salzberg
4. Aditi H. Chaubey
5. R. Aaron Bola
6. Jonathon R. Hoffman
7. Morgan L. Endreson
8. Renee M. Miller
9. Noah J. Reger
10. Douglas S. Portman
11. Denise M. Ferkey
12. Elad Schneidman
13. Meital Oren-Suissa

Reviewed by preLights

High-Throughput Aminoacyl-tRNA Synthetase Engineering for Genetic Code Expansion in Yeast

1. Jessica T. Stieglitz
2. James A. Van Deventer

Reviewed by preLights