Showing page 6 of 76 pages of list content

  1. Caveolin-1 regulates context-dependent signaling and survival in Ewing sarcoma

    This article has 25 authors:
    1. Dagan Segal
    2. Xiaoyu Wang
    3. Hanieh Mazloom-Farisbaf
    4. Felix Y. Zhou
    5. Divya Rajendran
    6. Erin Butler
    7. Bingying Chen
    8. Bo-Jui Chang
    9. Khushi Ahuja
    10. Averi Perny
    11. Kushal Bhatt
    12. Dana Kim Reed
    13. Diego H. Castrillon
    14. Jeon Lee
    15. Elise Jeffery
    16. Lei Wang
    17. Khai Nguyen
    18. Noelle S. Williams
    19. Stephen X. Skapek
    20. Satwik Rajaram
    21. Reto Fiolka
    22. Khuloud Jaqaman
    23. Gary Hon
    24. James F. Amatruda
    25. Gaudenz Danuser

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  2. Structural insights into mitotic-centrosome assembly

    This article has 15 authors:
    1. Nada Mohamad
    2. Siu-Shing Wong
    3. Anupa Majumdar
    4. Alan Wainman
    5. Ingelise Holland-Kaye
    6. Lars Hubatsch
    7. Zsofia Novak
    8. Andrey Pozniakovsky
    9. Martine Ruer-Gruss
    10. Andreas F.M. Haensele
    11. Anna Caballe
    12. Steven Johnson
    13. Susan M. Lea
    14. Anthony Hyman
    15. Jordan W. Raff

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  3. Cell size modulates ferroptosis susceptibility

    This article has 5 authors:
    1. Evgeny Zatulovskiy
    2. Magdalena B Murray
    3. Shuyuan Zhang
    4. Scott J Dixon
    5. Jan M Skotheim
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This important study highlights how cell size influences various cellular responses, with a particular focus on ferroptosis. The evidence presented is convincing, employing multiple model systems and experimental approaches to support the conclusions. This work will be of significant interest to the fields of cell size, ferroptosis, and cancer biology.

      [Editors' note: this paper was reviewed by Review Commons.]

    Reviewed by eLife, Review Commons

    This article has 9 evaluationsAppears in 2 listsLatest version Latest activity
  4. Metabolic Trans-Omic Analysis Reveals Key Regulatory Disruption of Energy Metabolism in Alzheimer’s Disease

    This article has 5 authors:
    1. Tomoharu Katayama
    2. Hikaru Sugimoto
    3. Keigo Morita
    4. Hirohisa Watanabe
    5. Shinya Kuroda
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study presents a useful application of trans-omic network analyses to existing human brain datasets, generating systems-level insights into metabolic dysregulation in Alzheimer's disease. Overall, the authors' analytical choices are solid, with appropriate use of existing data and methods, and with many of their results confirming previous findings. However, some of the authors' key claims, related to previously unknown details of regulatory relationships, are only partially supported due to limitations in dataset cell-type resolution and network robustness, as well as a lack of functional validation. This work will be of interest to cellular or systems neurobiologists studying Alzheimer's disease and could serve as a helpful starting point for future work.

      [Editors' note: this paper was reviewed by Review Commons.]

    Reviewed by eLife, Review Commons

    This article has 7 evaluationsAppears in 2 listsLatest version Latest activity
  5. Nrf2 promotes thyroid development and hormone synthesis

    This article has 10 authors:
    1. Gillotay Pierre
    2. Romitti Mirian
    3. Dassy Benjamin
    4. Haerlingen Benoit
    5. Parakkal Shankar Meghna
    6. Faria Fonseca Barbara
    7. Ziros G. Panos
    8. Pal Singh Sumeet
    9. Sykiotis P. Gerasimos
    10. Costagliola Sabine

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  6. Five-layer systems analysis of Leishmania stage differentiation reveals an essential role for protein degradation in parasite development

    This article has 16 authors:
    1. Pascale Pescher
    2. Thibaut Douché
    3. Quentin Giai-Gianetto
    4. Karen Druart
    5. Julie Kovarova
    6. Blaise Li
    7. Thomas Cokelaer
    8. K Shanmugha Rajan
    9. Laura Piel
    10. Céline Besse
    11. Anne Boland
    12. Jean-François Deleuze
    13. Mariette Matondo
    14. Michael P Barrett
    15. Shulamit Michaeli
    16. Gerald F Späth
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This important study provides a comprehensive multi-omics characterization of Leishmania donovani stage differentiation, offering insights into the molecular basis of parasite adaptation across host environments. The authors present convincing evidence that stage transitions are not driven by genomic variation but instead rely on coordinated post-transcriptional regulation, including mRNA turnover, translation, and protein degradation. Although experimental validation of these findings and conclusions remains to be completed, the integration of diverse, high-quality datasets establishes a robust resource that will be of broad utility to researchers investigating Leishmania biology and life-cycle progression.

      [Editors' note: this paper was reviewed by Review Commons.]

    Reviewed by eLife, Review Commons

    This article has 15 evaluationsAppears in 2 listsLatest version Latest activity
  7. FuChi: A cell cycle biosensor for investigating cell-cycle kinetics during avian development

    This article has 24 authors:
    1. Zoe R. Sudderick
    2. Tiernan Briggs
    3. Shirooza Mubarak
    4. Melinda Van Kerckvoorde
    5. Ana R. Hernandez-Rodriguez
    6. Sudeepta K. Panda
    7. Jon Riddell;
    8. Cameron Batho-Samblas
    9. Lorna Taylor
    10. Lynn McTeir
    11. Dominique Meunier
    12. Amy Findlay
    13. Flossie Roberts
    14. Anna Raper
    15. Asako Sakaue-Sawano
    16. Atsushi Miyawaki
    17. Joe Rainger
    18. Jeffrey J. Schoenebeck
    19. Cornelis J. Weijer
    20. Mike J. McGrew
    21. Denis J. Headon
    22. Megan G. Davey
    23. Richard L. Mort
    24. James D. Glover

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity