Evaluated articles

C is non-coding genetic variation drives gene expression changes in the E. coli and P. aeruginosa pangenomes

1. Bamu F. Damaris
2. Matylda Zietek
3. Jelena Erdmann
4. Athanasios Typas
5. Susanne Häußler
6. Marco Galardini

Reviewed by Review Commons

The UAP56 mRNA Export Factor is Required for Dendrite and Synapse Pruning via Actin Regulation in Drosophila

1. Samuel Matthew Frommeyer
2. Ulrike Gigengack
3. Sandra Rode
4. Matthew Davies
5. Sebastian Rumpf

Reviewed by Review Commons

Fission yeast cells use distinct cell size control mechanisms for size adaptation to osmotic, oxidative, or low glucose conditions

1. Elena J. Cabral
2. Pablo Andres
3. Geraldin Argandona
4. Paige Duggan
5. Benjamin M. Kuran
6. Kristi E. Miller

Reviewed by Review Commons

Unlocking new understanding of Plasmodium sporozoite biology with expansion microscopy

1. Benjamin Liffner
2. Thiago Luiz Alves e Silva
3. Elizabeth Glennon
4. Veronica Primavera
5. Elaine Hoffman
6. Alexis Kaushansky
7. Joel Vega-Rodriguez
8. Sabrina Absalon

Reviewed by Review Commons

Heterochronic scaling of neurogenesis for species-specific dosing of cortical excitatory subtypes

1. Yuki Y. Yamauchi
2. Xuanhao D. Sheu
3. Rafat Tarfder
4. Takuma Kumamoto
5. Jun Hatakeyama
6. Haruka Sato
7. Pauline Rouillard
8. Merve Bilgic
9. Shuto Deguchi
10. Tomonori Nakamura
11. Yusuke Kishi
12. Kazuo Emoto
13. Ikuo K. Suzuki

Reviewed by Review Commons

Functional Profiling of 2,193 ASS1 Missense Variants: Insights into Variant Pathogenicity and Epistatic Interactions in Citrullinemia Type I

1. Russell S. Lo
2. Gareth A. Cromie
3. Michelle Tang
4. Amy Sirr
5. Ljubica Caldovic
6. Hiroki Morizono
7. Nicholas Ah Mew
8. Andrea Gropman
9. Aimée M. Dudley

Reviewed by Review Commons

IP3R2 mediated inter-organelle Ca ²⁺ signaling orchestrates melanophagy

1. Suman Saurav
2. Rajender K Motiani

Reviewed by Review Commons

The Hok bacterial toxin: diversity, toxicity, distribution and genomic localization

1. Andrés Escalera-Maurer
2. Adriana Messineo
3. Thibaud T. Renault
4. Elena Nicollin
5. Erika Castaneda-Sastre
6. Matthieu Brunot
7. Cléo Berrehail
8. Anaïs Le Rhun

Reviewed by Review Commons

Dynamics of bicoid mRNA localisation and translation dictate morphogen gradient formation

1. T. Athilingam
2. E.L. Wilby
3. P. Bensidoun
4. A. Trullo
5. M. Verbrugghe
6. X. Shi
7. M. Lagha
8. T.E. Saunders
9. T.T. Weil

Reviewed by Review Commons

Interpreting the Effects of DNA Polymerase Variants at the Structural Level Using MAVISp and Molecular Dynamics Simulations

1. Matteo Arnaudi
2. Karolina Krzesińska
3. Ludovica Beltrame
4. Pablo Sánchez-Izquierdo Besora
5. Matteo Tiberti
6. Mef Nilbert
7. Anna Rohlin
8. Elena Papaleo

Reviewed by Review Commons

Non-synaptic exocytosis along the axon shaft and its regulation by the submembrane periodic skeleton

1. Theresa Wiesner
2. Christopher Parperis
3. Fanny Boroni-Rueda
4. Nicolas Jullien
5. Afonso Mendes
6. Léa Marie
7. Louisa Mezache
8. Marie-Jeanne Papandréou
9. Ricardo Henriques
10. Christophe Leterrier

Reviewed by Review Commons

Specialization of ubiquitin ligases to distinct nucleic acid sensors

1. Ibrahim Syed
2. Sheng Chen
3. David J. Peeler
4. Paul F. McKay
5. Marco A. Briones-Orta
6. Jennifer A. Bohn
7. Robin J. Shattock
8. Daniel Gonçalves-Carneiro

Reviewed by Review Commons

The environmental stress response controls the biophysical properties of the cytoplasm and is critical for survival in quiescence

1. Lorena Kronig
2. Carmen A. Weber
3. Pablo Aurelio Gómez-García
4. Jonas S. Fischer
5. Christian Doerig
6. Agnès Michel
7. Paolo Ronchi
8. Sarah Khawaja
9. Paola Picotti
10. Benoît Kornmann
11. Karsten Weis

Reviewed by Review Commons

Drosophila host defense mechanisms against filamentous fungal pathogens with diverse lifestyles

1. Guiqing Liu
2. Yao Tian
3. Mark Austin Hanson
4. Prince Kumar Sah
5. Jun Li
6. Bruno Lemaitre

Reviewed by Review Commons

A genotype-phenotype transformer to assess and explain polygenic risk

1. Ingoo Lee
2. Zachary S. Wallace
3. Yuqi Wang
4. Sungjoon Park
5. Hojung Nam
6. Amit R. Majithia
7. Trey Ideker

Reviewed by Review Commons

Genetic and environmental determinants of multicellular-like phenotypes in fission yeast

1. Bence Kӧvér
2. Céleste E. Cohen
3. Markus Ralser
4. Benjamin M. Heineike
5. Jürg Bähler

Reviewed by Review Commons

Plasmin activity and sterile inflammation synergize to promote lethal embryonic liver degeneration

1. Meng-Ling Wu
2. Courtney T. Griffin

Reviewed by Review Commons

Large-scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of α-synuclein aggregation

1. Sandesh Neupane
2. Lea Nikolić
3. Lorenzo Maraio
4. Thomas Goiran
5. Nathan Karpilovsky
6. Stefano Sellitto
7. Vangelis Bouris
8. Jiang-An Yin
9. Ronald Melki
10. Edward A. Fon
11. Elena De Cecco
12. Adriano Aguzzi

Reviewed by Review Commons

Contractile peri-nuclear actomyosin network repositions peripheral and polar chromosomes to promote early kinetochore–microtubule interactions

1. Nooshin Sheidaei
2. John K. Eykelenboom
3. Zuojun Yue
4. Graeme Ball
5. Alexander J.R. Booth
6. Tomoyuki U. Tanaka

• Curated by eLife

  eLife Assessment

  This important study demonstrates that a peri-nuclear actomyosin network, present in some types of human cells, facilitates kinetochore-spindle attachment of chromosomes in unfavorable locations - thereby suppressing their missegregation rate. This actomyosin network and its general role have been studied previously, but this study convincingly clarifies the underlying mechanism using a light-controlled perturbation and detailed tracking of kinetochore movement. The generality of the mechanism could be further supported by confirming the findings in non-synchronized cells and additional cell lines. The results may have implications for understanding chromosome missegregation in cancer cells.

  [Editors' note: this paper was reviewed by Review Commons.]

Reviewed by eLife, Review Commons

Natural Killer Cell Receptor Signaling and Activation Depend on Cell Cycle Stages

1. Darren Wethington
2. Indrani Nayak
3. Helle Jensen
4. William C. Stewart
5. Oscar A. Aguilar
6. Shih-Yu Chen
7. Garry P. Nolan
8. Gregory K. Behbehani
9. Lewis L. Lanier
10. Jayajit Das

Reviewed by Review Commons