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  1. Histone methyltransferase DOT1L differentially affects the development of dendritic cell subsets

    This article has 15 authors:
    1. Rianne G. Bouma
    2. Willem-Jan de Leeuw
    3. Aru Z. Wang
    4. Muddassir Malik
    5. Joeke G.C. Stolwijk
    6. Veronique A.L. Konijn
    7. Anne Mensink
    8. Natalie Proost
    9. Maarten K. Nijen Twilhaar
    10. Tibor van Welsem
    11. Negisa Seyed Toutounchi
    12. Alsya J. Affandi
    13. Jip T. van Dinter
    14. Fred van Leeuwen
    15. Joke M.M. den Haan

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  2. Rab11B is required for binding and entry of recent H3N2, but not H1N1, influenza A isolates

    This article has 15 authors:
    1. Allyson H. Turner
    2. Sara A. Jaffrani
    3. Hannah C. Kubinski
    4. Deborah P. Ajayi
    5. Matthew B. Owens
    6. Conor D. Fanuele
    7. Madeline P. McTigue
    8. Cailey L. Appenzeller
    9. Addington Bowling
    10. Hannah W. Despres
    11. Madaline M. Schmidt
    12. Dave J. Shirley
    13. Jessica W. Crothers
    14. Ramiro Barrantes-Reynolds
    15. Emily A. Bruce

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  3. Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins

    This article has 8 authors:
    1. Roberta Carloni
    2. Tadhg Devlin
    3. Pin Tong
    4. Christos Spanos
    5. Tanya Auchynnikava
    6. Juri Rappsilber
    7. Keith R Matthews
    8. Robin C Allshire
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This work significantly advances our understanding of chromatin organization within regions of repetitive sequences in the parasitic protozoan Trypanosoma brucei. Using cutting edge interdisciplinary tools, the authors provide compelling evidence for two discrete types of repetitive DNA element-associated proteins- one set involved in essential centromere function; and, the other involved in glycoprotein antigenic variation via homologous recombination. Thus, these fundamental findings have implications for this parasite's biology, and for therapeutic targeting in kinetoplastid diseases. This work will be exciting to those in the centromere/mitosis and parasite immunity fields.

    Reviewed by eLife, Review Commons

    This article has 6 evaluationsAppears in 2 listsLatest version Latest activity