Evaluated articles

A Randomized Phase 2/3 Study of Ensitrelvir, a Novel Oral SARS-CoV-2 3C-Like Protease Inhibitor, in Japanese Patients with Mild-to-Moderate COVID-19 or Asymptomatic SARS-CoV-2 Infection: Results of the Phase 2a Part

1. Hiroshi Mukae
2. Hiroshi Yotsuyanagi
3. Norio Ohmagari
4. Yohei Doi
5. Takumi Imamura
6. Takuhiro Sonoyama
7. Takahiro Fukuhara
8. Genki Ichihashi
9. Takao Sanaki
10. Keiko Baba
11. Yosuke Takeda
12. Yuko Tsuge
13. Takeki Uehara

Reviewed by ScreenIT

Tixagevimab/cilgavimab pre-exposure prophylaxis is associated with lower breakthrough infection risk in vaccinated solid organ transplant recipients during the omicron wave

1. Ayman Al Jurdi
2. Leela Morena
3. Mariesa Cote
4. Emily Bethea
5. Jamil Azzi
6. Leonardo V. Riella

Reviewed by ScreenIT

Unmet Dental Needs in Children Following Suspension of School‐Based Oral Health Services Due to COVID ‐19

1. Ryan R. Ruff
2. Tamarinda J. Barry Godín
3. Rachel Whittemore
4. Topaz Murray Small
5. Nydia Santiago‐Galvin
6. Priyanka Sharma

Reviewed by ScreenIT

Multi-omic comparative analysis of COVID-19 and bacterial sepsis-induced ARDS

1. Richa Batra
2. William Whalen
3. Sergio Alvarez-Mulett
4. Luis G. Gomez-Escobar
5. Katherine L. Hoffman
6. Will Simmons
7. John Harrington
8. Kelsey Chetnik
9. Mustafa Buyukozkan
10. Elisa Benedetti
11. Mary E. Choi
12. Karsten Suhre
13. Edward Schenck
14. Augustine M. K. Choi
15. Frank Schmidt
16. Soo Jung Cho
17. Jan Krumsiek

Reviewed by ScreenIT

Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccination

1. Grace Kenny
2. Riya Negi
3. Sophie O'Reilly
4. Alejandro Garcia-Leon
5. Dana Alalwan
6. Colette Marie Gaillard
7. Gurvin Saini
8. Rosana Inzitari
9. Eoin R. Feeney
10. Obada Yousif
11. Aoife G Cotter
12. Eoghan de Barra
13. Corinna Sadlier
14. Fiona Crispie
15. Peter Doran
16. Virginie Gautier
17. Patrick W.G. Mallon

Reviewed by ScreenIT

Adaptation‐Proof SARS‐CoV‐2 Vaccine Design

1. Yashavantha L. Vishweshwaraiah
2. Brianna Hnath
3. Brendan Rackley
4. Jian Wang
5. Abhinay Gontu
6. Morgan Chandler
7. Kirill A. Afonin
8. Suresh V. Kuchipudi
9. Neil Christensen
10. Neela H. Yennawar
11. Nikolay V. Dokholyan

Reviewed by ScreenIT

Jinhua Qinggan granules for non-hospitalized COVID-19 patients: A double-blind, placebo-controlled, and randomized controlled trial

1. Muhammad Raza Shah
2. Samreen Fatima
3. Sehrosh Naz Khan
4. Shafi Ullah
5. Gulshan Himani
6. Kelvin Wan
7. Timothy Lin
8. Johnson Y. N. Lau
9. Qingquan Liu
10. Dennis S. C. Lam

Reviewed by ScreenIT

United States’ political climates and the spread of SARS-2-COVID-19 during 2020

1. Felicia Pratto
2. Andrew Cortopassi
3. Natasza Marrouch

Reviewed by ScreenIT

Antibody Response to SARS-CoV-2 among COVID-19 Confirmed Cases and Correlates with Neutralizing Assay in a Subgroup of Patients in Delhi National Capital Region, India

1. Puneet Misra
2. Shashi Kant
3. Randeep Guleria
4. Sanjay K. Rai
5. Abhishek Jaiswal
6. Suprakash Mandal
7. Guruprasad R. Medigeshi
8. Mohammad Ahmad
9. Anisur Rahman
10. Meenu Sangral
11. Kapil Yadav
12. Mohan Bairwa
13. Partha Haldar
14. Parveen Kumar

Reviewed by ScreenIT

Variation in the ACE2 receptor has limited utility for SARS-CoV-2 host prediction

1. Nardus Mollentze
2. Deborah Keen
3. Uuriintuya Munkhbayar
4. Roman Biek
5. Daniel G Streicker

• Curated by eLife

  Evaluation Summary:

  This important study shows that methods currently used to predict which animals species might be at risk of infection by SARS-CoV-2, by looking at features of the host cell receptor the virus binds to, are fundamentally flawed, with exceptionally strong support for this conclusion. Much work on the potential host range of SARS-CoV-2 has focused on measuring the susceptibility of different species' ACE2 receptors to sarbecovirus entry and extending predictions to other unmeasured species based on ACE2 sequence features. Mollentze and colleagues show that ACE2 sequences are not more than a proxy for generic species relationships. In other words, species phylogeny alone can provide equivalent predictive power, allowing for predictions of mammalian susceptibility to sarbecovirus infection for the many species for which ACE2 sequences are not known yet.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

Reviewed by eLife, ScreenIT

A hybrid approach to predict COVID-19 cases using neural networks and inverse problem

1. Subhendu Paul
2. Emmanuel Lorin

Reviewed by ScreenIT

What are effective strategy to constrain COVID-19 pandemic crisis? lessons learned from a comparative policy analysis between Italian regions to cope with next pandemic impact

1. Mario Coccia
2. Igor Benati

Reviewed by ScreenIT

Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest

1. Georg Hahn
2. Sanghun Lee
3. Dmitry Prokopenko
4. Jonathan Abraham
5. Tanya Novak
6. Julian Hecker
7. Michael Cho
8. Surender Khurana
9. Lindsey R. Baden
10. Adrienne G. Randolph
11. Scott T. Weiss
12. Christoph Lange

Reviewed by ScreenIT

Differential Evasion of Delta and Omicron Immunity and Enhanced Fusogenicity of SARS-CoV-2 Omicron BA.4/5 and BA.2.12.1 Subvariants

1. Panke Qu
2. Julia N. Faraone
3. John P. Evans
4. Xue Zou
5. Yi-Min Zheng
6. Claire Carlin
7. Joseph S. Bednash
8. Gerard Lozanski
9. Rama K. Mallampalli
10. Linda J. Saif
11. Eugene M. Oltz
12. Peter J. Mohler
13. Richard J. Gumina
14. Shan-Lu Liu

Reviewed by ScreenIT

Racial differences in vaccine acceptance in a rural southern US state

1. Benjamin C. Amick
2. Jaimi L. Allen
3. Clare C. Brown
4. Anthony Goudie
5. Mick Tilford
6. Mark Williams

Reviewed by ScreenIT

Prophylactic treatment of Glycyrrhiza glabra mitigates COVID-19 pathology through inhibition of pro-inflammatory cytokines in the hamster model and NETosis

1. Zaigham Abbas Rizvi
2. Prabhakar Babele
3. Srikanth Sadhu
4. Upasna Madan
5. Manas Ranjan Tripathy
6. Sandeep Goswami
7. Shailendra Mani
8. Sachin Kumar
9. Amit Awasthi
10. Madhu Dikshit

Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

The ATLAS™ screening assay reveals distinct CD4 ⁺ and CD8 ⁺ SARS-CoV-2 antigen response profiles which have implications to Omicron cellular immunity

1. James J. Foti
2. Kevin Lema
3. Justin Strickland
4. Emily Tjon
5. Adrienne Li
6. Amalia Rivera
7. Crystal Cabral
8. Laura Cormier
9. Louisa Dowal
10. Sudhir Rao
11. Vijetha Vemulapalli
12. Jessica B. Flechtner

Reviewed by ScreenIT

SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression

1. Najla Arshad
2. Maudry Laurent-Rolle
3. Wesam S. Ahmed
4. Jack Chun-Chieh Hsu
5. Susan M. Mitchell
6. Joanna Pawlak
7. Debrup Sengupta
8. Kabir H. Biswas
9. Peter Cresswell

Reviewed by ScreenIT

Neuropathic symptoms with SARS-CoV-2 vaccination

1. Farinaz Safavi
2. Lindsey Gustafson
3. Brian Walitt
4. Tanya Lehky
5. Sara Dehbashi
6. Amanda Wiebold
7. Yair Mina
8. Susan Shin
9. Baohan Pan
10. Michael Polydefkis
11. Anne Louise Oaklander
12. Avindra Nath

Reviewed by ScreenIT

Summaries, Analysis and Simulations of Recent COVID-19 Epidemic in Shanghai

1. Lequan Min

Reviewed by ScreenIT