Showing page 1 of 1 pages of list content

  1. Testing the ion-current model for flagellar length sensing and IFT regulation

    This article has 5 authors:
    1. Hiroaki Ishikawa
    2. Jeremy Moore
    3. Dennis R Diener
    4. Markus Delling
    5. Wallace F Marshall
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This paper is valuable and of interest to scientists studying primary cilia/flagellar formation and regulation. It addresses how ciliary/flagellar length is controlled and whether calcium negatively regulates Intraflagellar transport (IFT) injection. The study convincingly demonstrates that calcium influx correlates with flagellar length, but calcium does not appear to work as a negative regulator of IFT injection, which challenges a previous model. The models and methods are generally sound, but some conclusions would be strengthened by additional experimental support.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 3 listsLatest version Latest activity