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Structural and Functional Insights into Alkaline-pH Sensing by the Alka Channel

This article has 4 authors:
1. Tingwei Mi
2. Yuhang Wang
3. Yan Zhao
4. Yali V. Zhang
This article has no evaluationsAppears in 1 listLatest version Oct 30, 2025
Structural mechanisms of pump assembly and drug transport in the AcrAB-TolC efflux system

This article has 3 authors:
1. Xiaofei Ge
2. Zhiwei Gu
3. Jiawei Wang
This article has no evaluationsAppears in 1 listLatest version Oct 30, 2025
The molecular architecture of the aquaglyceroporin gating system in Saccharomyces cerevisiae

This article has 6 authors:
1. Mikael Andersson
2. Linde Viaene
3. Adeleine Marie Albalate
4. Mark C Leake
5. Adam Wollman
6. Sviatlana Shashkova
This article has no evaluationsAppears in 1 listLatest version Oct 24, 2025
Electrostatic Interaction Determines the Docking Specificity and the Formation of Functional Cx36 Gap Junction Channels

This article has 5 authors:
1. Robert S. Wong
2. Zhiyuan Song
3. Yu T. Zheng
4. Haiqing Zhao
5. Donglin Bai
This article has no evaluationsAppears in 1 listLatest version Oct 26, 2025
pH-dependent regulation in SLC38A9

This article has 3 authors:
1. Xuelang Mu
2. Ampon Sae Her
3. Tamir Gonen
This article has no evaluationsAppears in 1 listLatest version Oct 25, 2025
In Situ Structure Determination of a Membrane Protein in Native Cellular Membranes by Proton-Detected Solid-State NMR

This article has 10 authors:
1. Huayong Xie
2. Weijing Zhao
3. Hang Xiao
4. Yan Zhang
5. Yang Shen
6. Yuefang Gan
7. Qiong Tong
8. Yongxiang Zhao
9. Huan Tan
10. Jun Yang
This article has no evaluationsAppears in 1 listLatest version Oct 29, 2025
MDFIC2 is a sensory neuron-specific PIEZO channel auxiliary subunit

This article has 14 authors:
1. Zijing Zhou
2. Fei Dai
3. Delfine Cheng
4. Xiaonuo Ma
5. Seyedeh Farzaneh Omidkhoda
6. Jack Clarke
7. Huijing Zhang
8. Michael Laden
9. Yang Guo
10. Jinyuan Vero Li
11. Renjing Liu
12. Emily S Wong
13. Yixiao Zhang
14. Charles D Cox
This article has no evaluationsAppears in 1 listLatest version Oct 28, 2025
Opsins are Phospholipid Scramblases in All Domains of Life

This article has 6 authors:
1. Zachary A. Maschmann
2. David E. Hardy
3. Indu Menon
4. Jenna Webb
5. Anant K. Menon
6. Katrina T. Forest
This article has no evaluationsAppears in 1 listLatest version Aug 18, 2025
Molecular determinants of low affinity complexes formed by the electrical synapse proteins Connexin 36 and ZO-1

This article has 8 authors:
1. Stephan Tetenborg
2. Fatemeh Ariakia
3. Nikki Brantley
4. Georg Zoidl
5. Eyad Shihabeddin
6. Christophe P. Ribelayga
7. Tarsis G. Ferreira
8. John O’Brien
This article has no evaluationsAppears in 1 listLatest version Oct 27, 2025
Inhibition mechanism of pancreatic KATP channels by centipede toxins

This article has 5 authors:
1. Tianyi Hou
2. Mengmeng Wang
3. Yongmei Tan
4. Chengpeng Fan
5. Lei Chen
This article has no evaluationsAppears in 1 listLatest version Oct 27, 2025
Simulated 5-HT2A receptor activation accounts for the high complexity of brain activity during psychedelic states

This article has 3 authors:
1. Hugo M. Martin
2. Rodrigo Cofre
3. Alain Destexhe
This article has no evaluationsAppears in 1 listLatest version Oct 20, 2025
Nckx30c , a Drosophila K ⁺ -dependent Na ⁺ /Ca ²⁺ exchanger, regulates temperature-sensitive convulsions and age-related neurodegeneration

This article has 10 authors:
1. Al Nahian Khan Majlish
2. Sophia Bourgeois
3. Shu Hui Lye
4. Saul Landaverde
5. Emilia Cytron
6. Megan Cline
7. Harris Bolus
8. Robert N. Correll
9. Atulya Iyengar
10. Stanislava Chtarbanova
This article has no evaluationsAppears in 1 listLatest version Oct 9, 2025
Live-cell quantitative monitoring reveals distinct, high-affinity Gβγ regulations of GIRK2 and GIRK1/2 channels

This article has 19 authors:
1. Reem Handklo-Jamal
2. Tal Keren Raifman
3. Boris Shalomov
4. Patrick Hofer
5. Uri Kahanovitch
6. Theres Friesacher
7. Galit Tabak
8. Vladimir Tsemakhovich
9. Haritha P. Reddy
10. Orna Chomsky-Hecht
11. Debi Ranjan Tripathy
12. Kerstin Zuhlke
13. Carmen W. Dessauer
14. Enno Klussmann
15. Yoni Haitin
16. Joel A. Hirsch
17. Anna Stary-Weinzinger
18. Daniel Yakubovich
19. Nathan Dascal
This article has no evaluationsAppears in 1 listLatest version Oct 15, 2025
Multiple Allosteric Sites Allow for Synergistic Enhancement of GPCR Signaling

This article has 22 authors:
1. Kai Wang
2. Snezana T. Dimova
3. John N. Hanson
4. Abhishek Thakur
5. Youwei Xu
6. Yini Liu
7. Amy E. Moritz
8. Alexander Goldberg
9. Bing Xie
10. Jayachandra Rayadurgam
11. Feijun Wang
12. Ashley N. Nilson
13. Kathryn D. Luderman
14. R. Benjamin Free
15. Wen Hu
16. Jian Zhang
17. H. Eric Xu
18. Kevin J. Frankowski
19. Yue Wang
20. Lei Shi
21. David R. Sibley
22. Youwen Zhuang
This article has no evaluationsAppears in 1 listLatest version Oct 22, 2025
Hydration Network Drives Activation and G Protein Selectivity in GPR174

This article has 11 authors:
1. Ying-Jun Dong
2. Kun Xi
3. Ya-Zhi Zhang
4. Jian-Heng Xue
5. Dan-dan Shen
6. Shao-Kun Zang
7. Ruozhu Zhao
8. Hai Qi
9. Chunyou Mao
10. Wei-Wei Wang
11. Yan Zhang
This article has no evaluationsAppears in 1 listLatest version Oct 6, 2025
Role of Water Models in Simulations of Ion Conduction in Potassium Channels

This article has 5 authors:
1. Stefano Bosio
2. Diego Gazzoni
3. Carmen Domene
4. Matteo Masetti
5. Simone Furini
This article has no evaluationsAppears in 1 listLatest version Oct 25, 2025
Cryo-EM structure of CLCA1 identifies CLCA1 as a founding member of a novel metzincin family

This article has 8 authors:
1. Elisabeth Nyström
2. Sjoerd van der Post
3. Doireann Bradley Barrett
4. Grete Raba
5. Thaher Pelaseyed
6. Mihai Oltean
7. Ana S. Luis
8. Sergio Trillo-Muyo
This article has no evaluationsAppears in 1 listLatest version Oct 18, 2025
Structure of the G _q -coupled adhesion receptor ADGRL4, a GPCR implicated in cancer

This article has 7 authors:
1. Qingchao Chen
2. Anastasiia Gusach
3. Aurora Diamante
4. Jayesh C. Patel
5. Patricia C. Edwards
6. Christopher G. Tate
7. David M. Favara
This article has no evaluationsAppears in 1 listLatest version Oct 5, 2025
A neurotensin receptor type 1-derived pepducin acts as a biased allosteric modulator to regulate target receptor function

This article has 14 authors:
1. Rebecca L. Brouillette
2. Frédérique Lussier
3. Émile Breault
4. Nathan Meneboo
5. Magali Chartier
6. Élora Midavaine
7. Jérôme Côté
8. Véronique Blais
9. Christine E. Mona
10. Jean-Michel Longpré
11. Michel Grandbois
12. Martin Audet
13. Élie Besserer-Offroy
14. Philippe Sarret
This article has no evaluationsAppears in 1 listLatest version Oct 15, 2025
Structure-guided allosteric modulation of the delta opioid receptor

This article has 18 authors:
1. Jesse I. Mobbs
2. M. Deborah Nguyen
3. Owindeep Deo
4. Damian Bartuzi
5. Hariprasad Venugopal
6. Sadia Alvi
7. Vi Pham
8. Nick Barnes
9. Arthur Christopoulos
10. Daniel P. Poole
11. Simona E. Carbone
12. Manuela Jörg
13. Ben Capuano
14. Jens Carlsson
15. Arisbel B. Gondin
16. Peter J. Scammells
17. Celine Valant
18. David M. Thal
This article has no evaluationsAppears in 1 listLatest version Oct 17, 2025

Reading List

Structural and Functional Insights into Alkaline-pH Sensing by the Alka Channel

Structural mechanisms of pump assembly and drug transport in the AcrAB-TolC efflux system

The molecular architecture of the aquaglyceroporin gating system in Saccharomyces cerevisiae

Electrostatic Interaction Determines the Docking Specificity and the Formation of Functional Cx36 Gap Junction Channels

pH-dependent regulation in SLC38A9

In Situ Structure Determination of a Membrane Protein in Native Cellular Membranes by Proton-Detected Solid-State NMR

MDFIC2 is a sensory neuron-specific PIEZO channel auxiliary subunit

Opsins are Phospholipid Scramblases in All Domains of Life

Molecular determinants of low affinity complexes formed by the electrical synapse proteins Connexin 36 and ZO-1

Inhibition mechanism of pancreatic KATP channels by centipede toxins

Simulated 5-HT2A receptor activation accounts for the high complexity of brain activity during psychedelic states

Nckx30c , a Drosophila K ⁺ -dependent Na ⁺ /Ca ²⁺ exchanger, regulates temperature-sensitive convulsions and age-related neurodegeneration

Live-cell quantitative monitoring reveals distinct, high-affinity Gβγ regulations of GIRK2 and GIRK1/2 channels

Multiple Allosteric Sites Allow for Synergistic Enhancement of GPCR Signaling

Hydration Network Drives Activation and G Protein Selectivity in GPR174

Role of Water Models in Simulations of Ion Conduction in Potassium Channels

Cryo-EM structure of CLCA1 identifies CLCA1 as a founding member of a novel metzincin family

Structure of the G _q -coupled adhesion receptor ADGRL4, a GPCR implicated in cancer

A neurotensin receptor type 1-derived pepducin acts as a biased allosteric modulator to regulate target receptor function

Structure-guided allosteric modulation of the delta opioid receptor