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Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelium Modify Seminal Plasma Components with Potential to Improve Sperm Motility

1. Takahiro Yamanaka
2. Zimo Xiao
3. Natsumi Tsujita
4. Mahmoud Awad
5. Takashi Umehara
6. Masayuki Shimada

• Curated by eLife

  eLife Assessment

  This important work elucidates the biological processes and detailed mechanisms by which testosterone influences seminal plasma metabolites in mice. The evidence supporting the upregulation of metabolic enzymes and the role of ACLY is solid, highlighting the potential contributions of fatty acids to sperm motility.

Reviewed by eLife