ScreenIT

Latest preprint reviews

1. Genome Scale-Differential Flux Analysis reveals deregulation of lung cell metabolism on SARS-CoV-2 infection

   This article has 2 authors:

   1. Piyush Nanda
   2. Amit Ghosh

   Reviewed by ScreenIT

2. Clinical validation of automated and rapid mariPOC SARS-CoV-2 antigen test

   This article has 8 authors:

   1. Juha M. Koskinen
   2. Petri Antikainen
   3. Kristina Hotakainen
   4. Anu Haveri
   5. Niina Ikonen
   6. Carita Savolainen-Kopra
   7. Kati Sundström
   8. Janne O. Koskinen

   Reviewed by ScreenIT

3. The Silent Pandemic COVID-19 in the Asymptomatic Population

   This article has 2 authors:

   1. Robert L. Stout
   2. Steven J. Rigatti

   Reviewed by ScreenIT

4. SARS‐CoV ‐2 in human milk is inactivated by Holder pasteurisation but not cold storage

   This article has 8 authors:

   1. Gregory J Walker
   2. Vanessa Clifford
   3. Nidhi Bansal
   4. Alberto O Stella
   5. Stuart Turville
   6. Sacha Stelzer‐Braid
   7. Laura D Klein
   8. William Rawlinson

   Reviewed by ScreenIT

5. Potential impact of intervention strategies on COVID-19 transmission in Malawi: a mathematical modelling study

   This article has 12 authors:

   1. Tara Mangal
   2. Charlie Whittaker
   3. Dominic Nkhoma
   4. Wingston Ng'ambi
   5. Oliver Watson
   6. Patrick Walker
   7. Azra Ghani
   8. Paul Revill
   9. Timothy Colbourn
   10. Andrew Phillips
   11. Timothy Hallett
   12. Joseph Mfutso-Bengo

   Reviewed by ScreenIT

6. Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation

   This article has 11 authors:

   1. Mart M Lamers
   2. Anna Z Mykytyn
   3. Tim I Breugem
   4. Yiquan Wang
   5. Douglas C Wu
   6. Samra Riesebosch
   7. Petra B van den Doel
   8. Debby Schipper
   9. Theo Bestebroer
   10. Nicholas C Wu
   11. Bart L Haagmans

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     This manuscript follows up on work documenting the relevance of the multi-basic cleavage site (MBCS) in the spike (S) protein of SARS-CoV-2 for determining cell tropism and mode of cell entry. The paper describes a number of important findings: 1) That SARS-CoV-2 grown in Vero cells rapidly acquires MBCS mutations, where as virus grown in airway epithelial cells or Vero-TMPRSSR2 cells do not; 2) that deep sequencing is necessary to see mutations emerging that are not apparent in consensus sequence reads; 3) that factors such as fetal calf serum can influence the selection of mutant phenotypes, and 4) that cultures derived from differentiated stem cells can provide reproducible systems for virus culture. Together, the work sets out clear guidelines for the propagation of SARS-CoV-2 to avoid adaptations to laboratory cell-lines/conditions and maintain the authenticity of clinical isolates. The work has relevance to other viruses and the use of permissive transformed cell lines.

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

   Reviewed by eLife, ScreenIT

7. Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity

   This article has 35 authors:

   1. Janie F. Shelton
   2. Anjali J. Shastri
   3. Chelsea Ye
   4. Catherine H. Weldon
   5. Teresa Filshtein-Sonmez
   6. Daniella Coker
   7. Antony Symons
   8. Jorge Esparza-Gordillo
   9. The 23andMe COVID-19 Team
   10. Adrian Chubb
   11. Alison Fitch
   12. Alison Kung
   13. Amanda Altman
   14. Andy Kill
   15. Jason Tan
   16. Jeff Pollard
   17. Jey McCreight
   18. Jess Bielenberg
   19. John Matthews
   20. Johnny Lee
   21. Lindsey Tran
   22. Michelle Agee
   23. Monica Royce
   24. Nate Tang
   25. Pooja Gandhi
   26. Raffaello d’Amore
   27. Ruth Tennen
   28. Scott Dvorak
   29. Scott Hadly
   30. Sungmin Park
   31. Taylor Morrow
   32. Trung Le
   33. Yiwen Zheng
   34. Stella Aslibekyan
   35. Adam Auton

   Reviewed by ScreenIT

8. Effect of large-scale testing platform in prevention and control of the COVID-19 pandemic: an empirical study with a novel numerical model

   This article has 21 authors:

   1. Qing Xie
   2. Jing Wang
   3. Jianling You
   4. Shida Zhu
   5. Rui Zhou
   6. Zhijian Tian
   7. Hao Wu
   8. Yang Lin
   9. Wei Chen
   10. Lan Xiao
   11. Xin Jin
   12. Jianjuan Li
   13. Jie Dong
   14. Honglong Wu
   15. Wei Zhang
   16. Jing Li
   17. Xun Xu
   18. Ye Yin
   19. Feng Mu
   20. Weijun Chen
   21. Wang Jian

   Reviewed by ScreenIT

9. Transferrin receptor is another receptor for SARS-CoV-2 entry

   This article has 16 authors:

   1. Xiaopeng Tang
   2. Mengli Yang
   3. Zilei Duan
   4. Zhiyi Liao
   5. Lei Liu
   6. Ruomei Cheng
   7. Mingqian Fang
   8. Gan Wang
   9. Hongqi Liu
   10. Jingwen Xu
   11. Peter M Kamau
   12. Zhiye Zhang
   13. Lian Yang
   14. Xudong Zhao
   15. Xiaozhong Peng
   16. Ren Lai

   Reviewed by ScreenIT

10. The potential health and economic value of SARS-CoV-2 vaccination alongside physical distancing in the UK: a transmission model-based future scenario analysis and economic evaluation

    This article has 51 authors:

    1. Frank G Sandmann
    2. Nicholas G Davies
    3. Anna Vassall
    4. W John Edmunds
    5. Mark Jit
    6. Fiona Yueqian Sun
    7. C Julian Villabona-Arenas
    8. Emily S Nightingale
    9. Alicia Showering
    10. Gwenan M Knight
    11. Katharine Sherratt
    12. Yang Liu
    13. Kaja Abbas
    14. Sebastian Funk
    15. Akira Endo
    16. Joel Hellewell
    17. Alicia Rosello
    18. Rachel Lowe
    19. Matthew Quaife
    20. Amy Gimma
    21. Oliver Brady
    22. Jack Williams
    23. Simon R Procter
    24. Rosalind M Eggo
    25. Yung-Wai Desmond Chan
    26. James D Munday
    27. Rosanna C Barnard
    28. Georgia R Gore-Langton
    29. Nikos I Bosse
    30. Naomi R Waterlow
    31. Charlie Diamond
    32. Timothy W Russell
    33. Graham Medley
    34. Stefan Flasche
    35. Katherine E Atkins
    36. Kiesha Prem
    37. David Simons
    38. Megan Auzenbergs
    39. Damien C Tully
    40. Christopher I Jarvis
    41. Kevin van Zandvoort
    42. Sam Abbott
    43. Carl A B Pearson
    44. Thibaut Jombart
    45. Sophie R Meakin
    46. Anna M Foss
    47. Adam J Kucharski
    48. Billy J Quilty
    49. Hamish P Gibbs
    50. Samuel Clifford
    51. Petra Klepac

    Reviewed by ScreenIT