Review Commons

Latest preprint reviews

1. Mitochondrial dysfunction heightens the integrated stress response to drive ALS pathogenesis

   This article has 8 authors:

   1. Curran Landry
   2. James Costanzo
   3. Miguel Mitne-Neto
   4. Mayana Zatz
   5. Ashleigh Schaffer
   6. Maria Hatzoglou
   7. Alysson Muotri
   8. Helen Cristina Miranda

   Reviewed by Review Commons

2. Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development

   This article has 7 authors:

   1. Theresa Schmid
   2. Gabriele Rodrian
   3. Elke Bachmann
   4. Alexander Kohler
   5. Michael Wegner
   6. Lina Gölz
   7. Matthias Weider

   Reviewed by Review Commons

3. Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility

   This article has 19 authors:

   1. Shivraj M Yabaji
   2. Vadim Zhernovkov
   3. Prasanna Babu Araveti
   4. Suruchi Lata
   5. Oleksii S Rukhlenko
   6. Salam Al Abdullatif
   7. Arthur Vanvalkenburg
   8. Yuriy O Alekseyev
   9. Qicheng Ma
   10. Gargi Dayama
   11. Nelson C Lau
   12. W Evan Johnson
   13. William R Bishai
   14. Nicholas A Crossland
   15. Joshua D Campbell
   16. Boris N Kholodenko
   17. Alexander A Gimelbrant
   18. Lester Kobzik
   19. Igor Kramnik

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     Yabaji et al. reports a fundamental study highlighting the mechanistic connection for susceptibility to TB infection via the sst1 locus, this was shown to involve increased IFN and Myc production causing the down-regulation of anti-oxidant defence genes and chronic lipidation. Ultimately, lipid peroxidation may underlie infectivity and macrophage dysfunction. Overall, the data presented are compelling, supported by a well designed multi-omics approach and the findings will be of broad interest to researchers investigating the molecular mechanisms of TB infection.

     [Editors' note: this paper was reviewed by Review Commons.]

   Reviewed by eLife, Review Commons

4. Dual-action peptide shuttles rescue Cu-amyloid-β-induced neurotoxicity and relocate Cu intracellularly

   This article has 8 authors:

   1. Michael Okafor
   2. David Schmitt
   3. Enrico Falcone
   4. Stéphane Gasman
   5. Laurent Raibaut
   6. Christelle Hureau
   7. Peter Faller
   8. Nicolas Vitale

   Reviewed by Review Commons

5. A conserved chronobiological complex times C. elegans development

   This article has 13 authors:

   1. Rebecca K. Spangler
   2. Kathrin Braun
   3. Guinevere E. Ashley
   4. Marit van der Does
   5. Daniel Wruck
   6. Andrea Ramos Coronado
   7. James Matthew Ragle
   8. Vytautas Iesmantavicius
   9. Lucas J. Morales Moya
   10. Keya Jonnalagadda
   11. Carrie L. Partch
   12. Helge Großhans
   13. Jordan D. Ward

   Reviewed by Review Commons

6. Plasma Membrane Remodelling in GM2 Gangliosidoses Drives Synaptic Dysfunction

   This article has 11 authors:

   1. Alex S. Nicholson
   2. David A. Priestman
   3. Robin Antrobus
   4. James C. Williamson
   5. Reuben Bush
   6. Henry G. Barrow
   7. Emily Smith
   8. Kostantin Dobrenis
   9. Nicholas A. Bright
   10. Frances M. Platt
   11. Janet E. Deane

   Reviewed by Review Commons

7. Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in Caenorhabditis elegans

   This article has 3 authors:

   1. Katsufumi Dejima
   2. Keita Yoshida
   3. Shohei Mitani

   Reviewed by Review Commons

8. Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS during glial injury signaling in Drosophila

   This article has 10 authors:

   1. Virág Vincze
   2. Zsombor Esküdt
   3. Erzsébet Fehér-Juhász
   4. Aishwarya Sanjay Chhatre
   5. András Jipa
   6. Martin Csordós
   7. Anna Rita Galambos
   8. Dalma Feil-Börcsök
   9. Gábor Juhász
   10. Áron Szabó

   Reviewed by Review Commons

9. TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence

   This article has 26 authors:

   1. Jennifer Kahlhofer
   2. Nikolas Marchet
   3. Brigitta Seifert
   4. Kristian Zubak
   5. Madlen Hotze
   6. Anna-Sophia Egger
   7. Claudia Manzl
   8. Yannick Weyer
   9. Sabine Weys
   10. Martin Offterdinger
   11. Sebastian Herzog
   12. Veronika Reiterer
   13. Marcel Kwiatkowski
   14. Saskia B. Wortmann
   15. Siamak Nemati
   16. Johannes A. Mayr
   17. Johannes Zschocke
   18. Bernhard Radlinger
   19. Kathrin Thedieck
   20. Lukas A. Huber
   21. Hesso Farhan
   22. Mariana E.G. de Araujo
   23. Susanne Kaser
   24. Sabine Scholl-Bürgi
   25. Daniela Karall
   26. David Teis

   Reviewed by Review Commons

10. Progressive chromosome shape changes quantified during cell divisions

    This article has 7 authors:

    1. Yasutaka Kakui
    2. Yoshiharu Kusano
    3. Tereza Clarence
    4. Maya Lopez
    5. Toru Hirota
    6. Bhavin S. Khatri
    7. Frank Uhlmann

    Reviewed by Review Commons