Review Commons

Latest preprint reviews

1. Trisomy 21 Impairs Synchronized Activity in Human Down Syndrome Cortical Excitatory Neuron Networks

   This article has 9 authors:

   1. Manuel Peter
   2. Raquel Real
   3. Alessio Strano
   4. Hugh P. C. Robinson
   5. Mark A. Smith
   6. Samuel J. Barnes
   7. Tania Dutta
   8. Vincenzo De Paola
   9. Frederick J. Livesey

   Reviewed by Review Commons

2. Microbiota impact Drosophila ageing via Acetobacter, Tachykinin, and TkR99D

   This article has 7 authors:

   1. Diana Marcu
   2. David R Sannino
   3. Anthony J Dornan
   4. Rita Ibrahim
   5. Atharv Kapoor
   6. Miriam Wood
   7. Adam J Dobson

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study demonstrates that in Drosophila melanogaster, tachykinin (Tk) expression is regulated by the microbiota. The authors present convincing evidence that axenic flies raised with no microbiota are longer-lived than conventionally reared animals, and that Tk expression and Tk receptors in the nervous system are required for this effect. They further test individual bacterial strains for their role in these effects and connect the effect to loss of lipid stores and suggest that FOXO may be involved in the phenotype, results that are of interest to the fields of environmental perception, host microbiome interactions, and geroscience.

     [Editors' note: this paper was reviewed by Review Commons.]

   Reviewed by eLife, Review Commons

3. Chronic replication stress-mediated genomic instability disrupts placenta development in mice

   This article has 4 authors:

   1. Mumingjiang Munisha
   2. Rui Huang
   3. Jordan Khan
   4. John C. Schimenti

   Reviewed by Review Commons

4. miR-184 modulates Ilp8 to control developmental timing during normal growth conditions and in response to developmental perturbations

   This article has 4 authors:

   1. Jervis Fernandes
   2. Muhammed Naseem
   3. Ayisha Marwa Mangattu Parambil
   4. Jishy Varghese

   Reviewed by Review Commons

5. The Ketogenic Diet Metabolite β-Hydroxybutyrate Promotes Mitochondrial Elongation via Deacetylation in HeLa Cells and Improves Autism-like Behavior in Zebrafish

   This article has 8 authors:

   1. Golam M. Uddin
   2. Rachel Lacroix
   3. Mashiat Zaman
   4. Iman Al Khatib
   5. Amit Jaiswal
   6. Jong M. Rho
   7. Deborah M. Kurrasch
   8. Timothy E. Shutt

   Reviewed by Review Commons

6. When mitochondria fall apart: Unbalanced mitochondrial segregation triggers loss of mtDNA in the absence of mitochondrial fusion

   This article has 8 authors:

   1. Lisa Dengler
   2. Francesco Padovani
   3. Bianca Lemke
   4. Rebecca Brugger
   5. Benedikt Westermann
   6. Boris Maček
   7. Kurt M. Schmoller
   8. Jennifer C. Ewald

   Reviewed by Review Commons

7. Interferon-β induction heterogeneity during KSHV infection is correlated to levels and activation of the transcription factors ATF2 and RelA, and not IRF3

   This article has 2 authors:

   1. Machika Kaku
   2. Marta Maria Gaglia

   Reviewed by Review Commons

8. We couldn't get details of this article at this time:
   10.1101/2025.01.13.632747

9. Assessing target genes for homing suppression gene drive

   This article has 8 authors:

   1. Xuejiao Xu
   2. Jialing Fang
   3. Jingheng Chen
   4. Jie Yang
   5. Xiaozhen Yang
   6. Shibo Hou
   7. Weitang Sun
   8. Jackson Champer

   Reviewed by Review Commons

10. E4BP4 Safeguards Brown Fat Mitochondria from Obesity-Induced Fragmentation via Ceramide Repression

    This article has 17 authors:

    1. Fernando Valdivieso-Rivera
    2. Vanessa O. Furino
    3. Carlos E. Leher
    4. Ariane M. Zanesco
    5. Monara Kaélle Cruz
    6. Flavia C. Gan
    7. Adriana Leandra Santoro
    8. Lara Regina-Ferreira
    9. Giovanna Leite Santos
    10. Tiago Gonçalves
    11. Luiz Osório Leiria
    12. Pedro M. Moraes-Vieira
    13. Roger Frigério Castilho
    14. Shingo Kajimura
    15. Marcelo A. Mori
    16. Licio A. Velloso
    17. Carlos H. Sponton

    Reviewed by Review Commons