Review Commons

Latest preprint reviews

1. Chromokinesin Klp-19 regulates microtubule overlap and dynamics during anaphase in C. elegans

   This article has 13 authors:

   1. Vitaly Zimyanin
   2. Magdalena Magaj
   3. Nadia Ingabire Manzi
   4. Che-Hang Yu
   5. Theresa Gibney
   6. Yu-Zen Chen
   7. Mustafa Basaran
   8. Xavier Horton
   9. Karsten Siller
   10. Ariel Pani
   11. Daniel Needleman
   12. Daniel J. Dickinson
   13. Stefanie Redemann

   Reviewed by Review Commons

2. Context specific ubiquitin modification of ribosomes regulates translation under oxidative stress

   This article has 6 authors:

   1. Shannon E. Dougherty
   2. Géssica C. Barros
   3. Matthew W. Foster
   4. Guoshou Teo
   5. Hyungwon Choi
   6. Gustavo M. Silva

   Reviewed by Review Commons

3. Temporally resolved single cell transcriptomics in a human model of amniogenesis

   This article has 9 authors:

   1. Nikola Sekulovski
   2. Amber E Carleton
   3. Anusha A Rengarajan
   4. Chien-Wei Lin
   5. Lauren L Juga
   6. Allison E Whorton
   7. Jenna Kropp Schmidt
   8. Thaddeus Golos
   9. Kenichiro Taniguchi

   Reviewed by Review Commons

4. Compensatory evolution to DNA replication stress is robust to nutrient availability

   This article has 2 authors:

   1. Mariana Natalino
   2. Marco Fumasoni

   Reviewed by Review Commons

5. A Dual Role for the PP2A Phosphatase in Hippo Signalling Regulation

   This article has 5 authors:

   1. Aashika Sekar
   2. Alberto Rizzo
   3. Elodie Sins
   4. Alexander D. Fulford
   5. Paulo S. Ribeiro

   Reviewed by Review Commons

6. Sex‐dimorphic gene regulation in murine macrophages across niches

   This article has 5 authors:

   1. Cassandra J McGill
   2. Olivia S White
   3. Ryan J Lu
   4. Nirmal K Sampathkumar
   5. Bérénice A Benayoun

   Reviewed by Review Commons

7. Dendritic atoh1a+ cells serve as Merkel cell precursors during skin development and regeneration

   This article has 12 authors:

   1. Evan W. Craig
   2. Erik C. Black
   3. Samantha Z. Fernandes
   4. Ahlan S. Ferdous
   5. Camille E. A. Goo
   6. Sheridan M. Sargent
   7. Elgene J. A. Quitevis
   8. Avery Angell Swearer
   9. Nathaniel G. Yee
   10. Jimann Shin
   11. Lilianna Solnica-Krezel
   12. Jeffrey P. Rasmussen

   Reviewed by Review Commons

8. Mitochondrial dysfunction heightens the integrated stress response to drive ALS pathogenesis

   This article has 8 authors:

   1. Curran Landry
   2. James Costanzo
   3. Miguel Mitne-Neto
   4. Mayana Zatz
   5. Ashleigh Schaffer
   6. Maria Hatzoglou
   7. Alysson Muotri
   8. Helen Cristina Miranda

   Reviewed by Review Commons

9. Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development

   This article has 7 authors:

   1. Theresa Schmid
   2. Gabriele Rodrian
   3. Elke Bachmann
   4. Alexander Kohler
   5. Michael Wegner
   6. Lina Gölz
   7. Matthias Weider

   Reviewed by Review Commons

10. Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility

    This article has 19 authors:

    1. Shivraj M Yabaji
    2. Vadim Zhernovkov
    3. Prasanna Babu Araveti
    4. Suruchi Lata
    5. Oleksii S Rukhlenko
    6. Salam Al Abdullatif
    7. Arthur Vanvalkenburg
    8. Yuriy O Alekseyev
    9. Qicheng Ma
    10. Gargi Dayama
    11. Nelson C Lau
    12. W Evan Johnson
    13. William R Bishai
    14. Nicholas A Crossland
    15. Joshua D Campbell
    16. Boris N Kholodenko
    17. Alexander A Gimelbrant
    18. Lester Kobzik
    19. Igor Kramnik

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      Yabaji et al. reports a fundamental study highlighting the mechanistic connection for susceptibility to TB infection via the sst1 locus, this was shown to involve increased IFN and Myc production causing the down-regulation of anti-oxidant defence genes and chronic lipidation. Ultimately, lipid peroxidation may underlie infectivity and macrophage dysfunction. Overall, the data presented are compelling, supported by a well designed multi-omics approach and the findings will be of broad interest to researchers investigating the molecular mechanisms of TB infection.

      [Editors' note: this paper was reviewed by Review Commons.]

    Reviewed by eLife, Review Commons