Review Commons

Latest preprint reviews

1. Key roles of the zona pellucida and perivitelline space in promoting gamete fusion and fast block to polyspermy inferred from the choreography of spermatozoa in mice oocytes

   This article has 10 authors:

   1. Yaëlle Dubois
   2. Sophie Favier
   3. Nathan Martin-Fornier
   4. Mohyeddine Omrane
   5. David Stroebel
   6. Eric Perez
   7. Sandrine Barbaux
   8. Ahmed Ziyyat
   9. Nicolas Rodriguez
   10. Christine Gourier

   Reviewed by Review Commons

2. Lipid packing contributes to the confinement of caveolae to the plasma membrane

   This article has 10 authors:

   1. Elin Larsson
   2. Aleksei Kabedev
   3. Hudson Pace
   4. Jakob Lindwall
   5. Fouzia Bano
   6. Robert G Parton
   7. Christel AS Bergström
   8. Ingela Parmryd
   9. Marta Bally
   10. Richard Lundmark

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study reports the important finding that the dynamin inhibitor Dyngo-4a broadly affects lipid packing and plasma membrane dynamics, independently of its action on dynamin. While solid computational, biophysical, and cell-based evidence supports this conclusion, there is incomplete support for the authors' main claim on the role of lipid packing in caveolae internalization, as the causal relationship remains unclear and direct analyses are lacking. With stronger evidence, this work would be of significant interest to cell biologists, biophysicists, and chemists interested in membrane remodeling and drug-membrane interactions.

     [Editors' note: this paper was reviewed by Review Commons.]

   Reviewed by eLife, Review Commons

3. TORC2-regulated sterol redistribution mediates recovery from membrane perturbation by small amphipathic molecules.

   This article has 7 authors:

   1. Maria G. Tettamanti
   2. Paulina Nowak
   3. Beata Kusmider
   4. Jennifer M Kefauver
   5. Vincent Mercier
   6. Aurelien Roux
   7. Robbie Loewith

   Reviewed by Review Commons

4. Engineering fluorescent reporters in human pluripotent cells and strategies for live imaging human neurogenesis

   This article has 8 authors:

   1. Alwyn Dady
   2. Lindsay Davidson
   3. Nicolas Loyer
   4. Sophie Rappich
   5. Greg Findlay
   6. Timothy Sanders
   7. Jens Januschke
   8. Kate G. Storey

   Reviewed by Review Commons

5. Antigen flexibility supports the avidity of hemagglutinin-specific antibodies at low antigen densities

   This article has 6 authors:

   1. Ananya Benegal
   2. Yuanyuan He
   3. Katilyn Ho
   4. Giselle Groff
   5. Zijian Guo
   6. Michael D. Vahey

   Reviewed by Review Commons

6. The microcephaly protein WDR62 regulates cellular purine metabolism through the HSP70/HSP90 chaperone machinery

   This article has 6 authors:

   1. Matthew J. Morris
   2. Yvonne Y. Yeap
   3. Chi Chen
   4. S. Sean Millard
   5. Julia K. Pagan
   6. Dominic C. H. Ng

   Reviewed by Review Commons

7. Recurrent cancer-associated ERBB4 mutations are transforming and confer resistance to targeted therapies

   This article has 15 authors:

   1. Veera K. Ojala
   2. Sini Ahonen
   3. Aura Tuohisto-Kokko
   4. Olaya Esparta
   5. Peppi Suominen
   6. Anne Jokilammi
   7. Iman Farahani
   8. Deepankar Chakroborty
   9. Nikol Dibus
   10. Steffen Boettcher
   11. Tomi T. Airenne
   12. Mark S. Johnson
   13. Lisa D. Eli
   14. Klaus Elenius
   15. Kari J. Kurppa

   Reviewed by Review Commons

8. The Arp2/3 complex maintains genome integrity and survival of epidermal Langerhans cells

   This article has 23 authors:

   1. Maria-Graciela Delgado
   2. Ann-Kathrin Burkhart
   3. Javiera Villar
   4. Roberto Amadio
   5. Vanessa S. Racz
   6. Doriane Sanséau
   7. Nilushi De Silva
   8. Livia Lacerda Mariano
   9. Anna Shmakova
   10. Anna Chipont
   11. Mabel San Roman
   12. Giulia Bracchetti
   13. Vincent Calmettes
   14. Zahraa Alraies
   15. Mathieu Maurin
   16. Aurelien Dauphin
   17. Coralie Guerin
   18. Florent Ginhoux
   19. Nicolas Manel
   20. Daniele Fachinetti
   21. Federica Benvenuti
   22. Sandra Iden
   23. Ana-Maria Lennon-Duménil

   Reviewed by Review Commons

9. Identification of Wnt regulated genes that are repressed by, or independent of, β-catenin

   This article has 6 authors:

   1. Shiyang Liu
   2. Sara Haghani
   3. Enrico Petretto
   4. Babita Madan
   5. Nathan Harmston
   6. David M Virshup

   Reviewed by Review Commons

10. Sulfation affects apical extracellular matrix organization during development of the Drosophila embryonic salivary gland tube

    This article has 6 authors:

    1. J Luke Woodward
    2. Jeffrey Matthew
    3. Rutuparna Joshi
    4. Vishakha Vishwakarma
    5. Ying Xiao
    6. SeYeon Chung

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This paper is important in demonstrating a requirement for sulfation in organizing apical extracellular matrix (aECM) during tubulogenesis in Drosophila melanogaster. The authors identify and characterize the organization of some of the first known components of the non-chitinous aECM in the Drosophila salivary gland tube, and these findings are supported by convincing data. This study would be of interest to developmental and cell biologists.

      [Editors' note: this paper was reviewed by Review Commons.]

    Reviewed by eLife, Review Commons