preLights

Latest preprint reviews

1. Modeling transcriptional profiles of gene perturbation with deep neural network

   This article has 4 authors:

   1. Wenke Liu
   2. Xuya Wang
   3. D R Mani
   4. David Fenyö

   Reviewed by preLights

2. The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites

   This article has 7 authors:

   1. Joelle Lo
   2. Katherine F. Vaeth
   3. Gurprit Bhardwaj
   4. Neelanjan Mukherjee
   5. Holger A. Russ
   6. Jeffrey K. Moore
   7. J. Matthew Taliaferro

   Reviewed by preLights

3. Engineered Nanotopographies Induce Transient Openings in the Nuclear Membrane

   This article has 17 authors:

   1. Einollah Sarikhani
   2. Vrund Patel
   3. Zhi Li
   4. Dhivya Pushpa Meganathan
   5. Keivan Rahmani
   6. Leah Sadr
   7. Ryan Hosseini
   8. Diether Visda
   9. Shivani Shukla
   10. Hamed Naghsh‐Nilchi
   11. Adarsh Balaji
   12. Gillian McMahon
   13. Shaoming Chen
   14. Johannes Schöneberg
   15. Colleen A. McHugh
   16. Lingyan Shi
   17. Zeinab Jahed

   Reviewed by preLights

4. Pharyngeal neuronal mechanisms governing sour taste perception in Drosophila melanogaster

   This article has 4 authors:

   1. Bhanu Shrestha
   2. Jiun Sang
   3. Suman Rimal
   4. Youngseok Lee

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This is a useful contribution to our understanding of taste perception. The idea that specific receptors function in the pharynx to mediate responses to carboxylic acids is interesting, although the expression analysis is incomplete. Reviewers also have a number of other suggestions for improvement, including the request that authors provide more details about the methodology used. In general, the claims are supported by solid evidence and add to a growing body of literature on this topic.

   Reviewed by eLife, preLights

5. Feedback regulation by the RhoA-specific GEF ARHGEF17 regulates actomyosin network disassembly

   This article has 5 authors:

   1. Vasundhara Rao
   2. Benjamin Grädel
   3. Lucien Hinderling
   4. Jakobus Van Unen
   5. Olivier Pertz

   Reviewed by preLights

6. Specialized signaling centers direct cell fate and spatial organization in a limb organoid model

   This article has 15 authors:

   1. Evangelia Skoufa
   2. Jixing Zhong
   3. Oliver Kahre
   4. Kelly Hu
   5. Georgios Tsissios
   6. Louise Carrau
   7. Antonio Herrera
   8. Albert Dominguez Mantes
   9. Alejandro Castilla-Ibeas
   10. Hwanseok Jang
   11. Martin Weigert
   12. Gioele La Manno
   13. Matthias Lutolf
   14. Marian Ros
   15. Can Aztekin

   Reviewed by preLights

7. The role of ER exit sites in maintaining P-body organization and transmitting ER stress response during Drosophila melanogaster oogenesis

   This article has 5 authors:

   1. Samantha N. Milano
   2. Livia V. Bayer
   3. Julie J. Ko
   4. Caroline E. Casella
   5. Diana P. Bratu

   Reviewed by preLights

8. Spiral-eyes: A soft active matter model of in vivo corneal epithelial cell migration

   This article has 4 authors:

   1. Kaja Kostanjevec
   2. Rastko Sknepnek
   3. Jon Martin Collinson
   4. Silke Henkes

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This useful study describes a physical mechanism for the emergence of spiral patterns in the outer epithelial layer of the mammalian cornea independent of pre-patterning or guidance cues, using an agent-based model of self-propelled particles with alignment. The model is well constructed, however the central premise of the manuscript, that the spiral patterning of epithelial corneal cells occurs without guidance cues, is incomplete and not fully supported. Several significant questions remain unanswered, such as the role of the corneal curvature or the importance of topological defects. Furthermore, comparison between the model and data are qualitative at best for the moment.

   Reviewed by eLife, preLights

9. Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA

   This article has 3 authors:

   1. Brett T. Wisniewski
   2. Jason C. Casler
   3. Laura L. Lackner

   Reviewed by preLights

10. Caudal fin shape imprinted during late zebrafish embryogenesis is re-patterned by the Sonic hedgehog pathway

    This article has 10 authors:

    1. Eric Surette
    2. Joan Donahue
    3. Crisvely Soto Martinez
    4. Stephanie Robinson
    5. Deirdre McKenna
    6. Brendan Fitzgerald
    7. Katherine Backus
    8. Rolf O. Karlstrom
    9. Nicolás Cumplido
    10. Sarah K. McMenamin

    Reviewed by preLights