preLights

Latest preprint reviews

1. Astrocytes close a motor circuit critical period

   This article has 4 authors:

   1. Sarah D. Ackerman
   2. Nelson A. Perez-Catalan
   3. Marc R. Freeman
   4. Chris Q. Doe

   Reviewed by preLights

2. Conditional Guide RNAs: Programmable Conditional Regulation of CRISPR/Cas Function in Bacterial and Mammalian Cells via Dynamic RNA Nanotechnology

   This article has 5 authors:

   1. Mikhail H. Hanewich-Hollatz
   2. Zhewei Chen
   3. Lisa M. Hochrein
   4. Jining Huang
   5. Niles A. Pierce

   Reviewed by preLights

3. Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites

   This article has 16 authors:

   1. Jesse V. Veenvliet
   2. Adriano Bolondi
   3. Helene Kretzmer
   4. Leah Haut
   5. Manuela Scholze-Wittler
   6. Dennis Schifferl
   7. Frederic Koch
   8. Léo Guignard
   9. Abhishek Sampath Kumar
   10. Milena Pustet
   11. Simon Heimann
   12. René Buschow
   13. Lars Wittler
   14. Bernd Timmermann
   15. Alexander Meissner
   16. Bernhard G. Herrmann

   Reviewed by preLights

4. Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane

   This article has 6 authors:

   1. James P. Zewe
   2. April M. Miller
   3. Sahana Sangappa
   4. Rachel C. Wills
   5. Brady D. Goulden
   6. Gerald R.V. Hammond

   Reviewed by preLights

5. An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens

   This article has 10 authors:

   1. Robert Coukos
   2. David Yao
   3. Mateo I Sanchez
   4. Eric T Strand
   5. Meagan E Olive
   6. Namrata D Udeshi
   7. Jonathan S Weissman
   8. Steven A Carr
   9. Michael C Bassik
   10. Alice Y Ting

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     Here authors present a robust, high-throughput and genome-wide strategy to identify genes that influence protein localization in individual subcellular compartments. The results profile subsets of genes that are involved in localization of tail-anchored proteins to mitochondrial and endoplasmic reticulum membranes and identify several unexpected regulators. This new tool is adaptable to studying various types of protein trafficking processes to shed light on their molecular mechanisms.

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1, Reviewer #2 and Reviewer #3 agreed to share their names with the authors.)

   Reviewed by eLife, preLights

6. Heterogeneity in collective endothelial cell behavior is a driver of arterio-venous remodeling

   This article has 4 authors:

   1. Keyi Jiang
   2. Cathy Pichol-Thievend
   3. Zoltan Neufeld
   4. Mathias Francois

   Reviewed by preLights

7. Cell patterning by secretion-induced plasma membrane flows

   This article has 8 authors:

   1. Veneta Gerganova
   2. Iker Lamas
   3. David M. Rutkowski
   4. Aleksandar Vještica
   5. Daniela Gallo Castro
   6. Vincent Vincenzetti
   7. Dimitrios Vavylonis
   8. Sophie G. Martin

   Reviewed by preLights

8. Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation

   This article has 6 authors:

   1. Hiroko Katsuno-Kambe
   2. Jessica L Teo
   3. Robert J Ju
   4. James Hudson
   5. Samantha J Stehbens
   6. Alpha S Yap

   Reviewed by preLights

9. Aberrant replication licensing drives Copy Number Gains across species

   This article has 10 authors:

   1. Patroula Nathanailidou
   2. Michalis Petropoulos
   3. Styliani Maxouri
   4. Eirini Kasselimi
   5. Ioanna Eleni Symeonidou
   6. Ourania Preza
   7. Iris Spiliopoulou-Sdougkou
   8. Vladimir Beneš
   9. Stavros Taraviras
   10. Zoi Lygerou

   Reviewed by preLights

10. On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis

    This article has 10 authors:

    1. Felix M. Key
    2. Veda D. Khadka
    3. Carolina Romo-González
    4. Kimbria J. Blake
    5. Liwen Deng
    6. Tucker C. Lynn
    7. Jean C. Lee
    8. Isaac M. Chiu
    9. Maria T. García-Romero
    10. Tami D. Lieberman

    Reviewed by preLights