preLights

Latest preprint reviews

1. Tandem Duplication of Serpin Genes Yields Functional Variation and Snake Venom Inhibitors

   This article has 6 authors:

   1. Meilyn S Ward
   2. Matthew L Holding
   3. Laura M Haynes
   4. Mark J Margres
   5. Marjorie D Matocq
   6. David Ginsburg

   Reviewed by preLights

2. Hsp70 is phosphorylated in a conserved response to DNA damage and contributes to cell cycle control

   This article has 6 authors:

   1. Thomas Moss
   2. Alexandra Wooldredge
   3. Koustav Bhakta
   4. Matthew Cronin
   5. Jason E Gestwicki
   6. Shaeri Mukherjee

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This potentially valuable manuscript focuses on the phosphorylation of residue T495 as a mechanism to inactivate HSP70 and disrupt cell cycle progression in response to DNA damage. The evidence supporting this model is solid, but would be significantly strengthened by additional studies defining the extent of T495 phosphorylation induced by DNA damage, identifying the kinase responsible for phosphorylating T495 of HSP70, and further elucidation of the functional implications of T495 phosphorylation in human cells. This work will be of interest to scientists focused on topics including chaperone biology, proteostasis, cell cycle progression, and DNA damage.

   Reviewed by eLife, preLights

3. The cold tolerance of an adult winter-active stonefly: how Allocapnia pygmaea (Plecoptera: Capniidae) avoids freezing in winter in Nova Scotia, Canada

   This article has 4 authors:

   1. Jona Lopez Pedersen
   2. Luke S. Burton
   3. Tamara M. Rodela
   4. Jantina Toxopeus

   Reviewed by preLights

4. In depth profiling of the cancer proteome from the flowthrough of standard RNA- preparation kits for precision oncology

   This article has 10 authors:

   1. Filip Mundt Madsen
   2. Annelaura Bach Nielsen
   3. Juanjuan Wang
   4. Josephine Kerzel Duel
   5. Christina Westmose Yde
   6. Martina Amnitzbøll Eriksen
   7. Ulrik Lassen
   8. Finn Cilius Nielsen
   9. Kristoffer Rohrberg
   10. Matthias Mann

   Reviewed by preLights

5. Lineage domains and cytoskeletal cables organize a cellular square grid in a crustacean

   This article has 6 authors:

   1. Beatrice L. Steinert
   2. Leo Blondel
   3. Chandrashekar Kuyyamudi
   4. Evangelia Stamataki
   5. Anastasios Pavlopoulos
   6. Cassandra G. Extavour

   Reviewed by preLights

6. Polyamine depletion inhibits norovirus infection by blocking virus-induced apoptosis

   This article has 7 authors:

   1. Maryna Chaika
   2. Heike Laschin
   3. Marina Pekelis
   4. Carmen Mirabelli
   5. Sandra Niendorf
   6. Christiane E. Wobus
   7. Stefan Taube

   Reviewed by preLights

7. Single-Cell Network Analysis Identifies CLEC4E as a Key Mediator of Proinflammatory mDC Responses in Influenza Infection

   This article has 8 authors:

   1. Subin Cho
   2. Gabriel Laghlali
   3. Arturo Marin
   4. Adolfo García-Sastre
   5. Gagandeep Singh
   6. Michael Schotsaert
   7. Won-Min Song
   8. Christian V. Forst

   Reviewed by preLights

8. RNA Structure Directs RNA Partitioning and is Actively Disrupted inside Stress Granules to Enable Cellular Recovery

   This article has 9 authors:

   1. Bowen Zhu
   2. Jovi Jian An Lim
   3. Yu Zhang
   4. Wen Ting Tan
   5. Jiayi Zhang
   6. Joy S Xiang
   7. Roland Huber
   8. Anthony Khong
   9. Yue Wan

   Reviewed by preLights

9. Targeting RhoA activity rejuvenates aged hematopoietic stem cells

   This article has 17 authors:

   1. Eva Mejía-Ramírez
   2. Pablo Iañez Picazo
   3. Barbara Walter
   4. Sara Montserrat-Vazquez
   5. Francesco Affuso
   6. Stefan Wieser
   7. Fabio Pezzano
   8. Loïc Reymond
   9. Jorge Castillo-Robles
   10. Francesca Matteini
   11. Loris Mularoni
   12. Dídac Maciá
   13. Ángel Raya
   14. Verena Ruprecht
   15. Yi Zheng
   16. Paula Petrone
   17. M. Carolina Florian

   Reviewed by preLights

10. Paclitaxel compromises nuclear integrity in interphase through SUN2-mediated cytoskeletal coupling

    This article has 5 authors:

    1. Thomas Hale
    2. Victoria L. Hale
    3. Piotr Kolata
    4. Ália dos Santos
    5. Matteo Allegretti

    Reviewed by preLights, Review Commons