Latest preprint reviews

  1. PUFFFIN: A novel, ultra-bright, customisable, single-plasmid system for labelling cell neighbourhoods

    This article has 4 authors:
    1. Tamina Lebek
    2. Mattias Malaguti
    3. Alistair Elfick
    4. Sally Lowell

    Reviewed by Review Commons, preLights

    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity
  2. Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

    This article has 10 authors:
    1. Mrityunjoy Kar
    2. Laura T. Vogel
    3. Gaurav Chauhan
    4. Hannes Ausserwöger
    5. Timothy J. Welsh
    6. Anjana R. Kamath
    7. Tuomas P. J. Knowles
    8. Anthony A. Hyman
    9. Claus A. M. Seidel
    10. Rohit V. Pappu

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  3. The genome of the colonial hydroid Hydractinia reveals that their stem cells use a toolkit of evolutionarily shared genes with all animals

    This article has 29 authors:
    1. Christine E. Schnitzler
    2. E. Sally Chang
    3. Justin Waletich
    4. Gonzalo Quiroga-Artigas
    5. Wai Yee Wong
    6. Anh-Dao Nguyen
    7. Sofia N. Barreira
    8. Liam B. Doonan
    9. Paul Gonzalez
    10. Sergey Koren
    11. James M. Gahan
    12. Steven M. Sanders
    13. Brian Bradshaw
    14. Timothy Q. DuBuc
    15. Febrimarsa
    16. Danielle de Jong
    17. Eric P. Nawrocki
    18. Alexandra Larson
    19. Samantha Klasfeld
    20. Sebastian G. Gornik
    21. R. Travis Moreland
    22. Tyra G. Wolfsberg
    23. Adam M. Phillippy
    24. James C. Mullikin
    25. Oleg Simakov
    26. Paulyn Cartwright
    27. Matthew Nicotra
    28. Uri Frank
    29. Andreas D. Baxevanis

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  4. TLR2 regulates hair follicle cycle and regeneration via BMP signaling

    This article has 10 authors:
    1. Luyang Xiong
    2. Irina Zhevlakova
    3. Xiaoxia Z West
    4. Detao Gao
    5. Rakhilya Murtazina
    6. Anthony Horak
    7. J Mark Brown
    8. Iuliia Molokotina
    9. Eugene A Podrez
    10. Tatiana V Byzova
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      Toll like receptor 2 (TLR2) signaling has traditionally been viewed a surface protein that induces innate immune responses and improves acquired immunity. Here, the authors suggest a different role for TLR2 in the hair cycle. By using a Cre reporter that is largely, but not solely active in hair follicle stem cells, the authors conditionally delete Tlr2 in mice and report that BMP signaling is sustained and hair cycle entry is delayed. Delving further, the authors identify CEP (2-ω-carboxyethyl pyrrole) as an endogenous ligand of TLR2 in hair follicle stem cell regulation. Although a role for TLR2 signaling in hair follicle stem cells is potentially novel and important, the reviewers remain in consensus that evidence presented in two significant areas continues to be incomplete: 1) where TLR2 and CEP are expressed and how specific is their expression to the hair follicle stem cells; 2) whether as the authors suggest, TLR2 functions by regulating BMP signaling in the stem cell niche of the hair follicle.

    Reviewed by eLife, preLights

    This article has 7 evaluationsAppears in 2 listsLatest version Latest activity
  5. Optical Control of G-Actin with a Photoswitchable Latrunculin

    This article has 13 authors:
    1. Nynke A. Vepřek
    2. Madeline H. Cooper
    3. Laura Laprell
    4. Emily Jie-Ning Yang
    5. Sander Folkerts
    6. Ruiyang Bao
    7. Malgorzata Boczkowska
    8. Nicholas J. Palmer
    9. Roberto Dominguez
    10. Thomas G. Oertner
    11. Liza A. Pon
    12. J. Bradley Zuchero
    13. Dirk H. Trauner

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  6. Hypoxia blunts angiogenic signaling and upregulates the antioxidant system in elephant seal endothelial cells

    This article has 6 authors:
    1. Kaitlin N Allen
    2. Julia María Torres-Velarde
    3. Juan Manuel Vazquez
    4. Diana D Moreno-Santillan
    5. Peter H Sudmant
    6. José Pablo Vázquez-Medina

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  7. Mechano-dependent sorbitol accumulation supports biomolecular condensate

    This article has 16 authors:
    1. Stephanie Torrino
    2. William M Oldham
    3. Andrés R Tejedor
    4. Ignacio S. Burgos
    5. Nesrine Rachedi
    6. Kéren Fraissard
    7. Caroline Chauvet
    8. Chaima Sbai
    9. Brendan P. O’Hara
    10. Sophie Abélanet
    11. Frederic Brau
    12. Stephan Clavel
    13. Rosana Collepardo-Guevara
    14. Jorge R. Espinosa
    15. Issam Ben-Sahra
    16. Thomas Bertero

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  8. CRISPR-dependent Base Editing Screens Identify Separation of Function Mutants of RADX with Altered RAD51 Regulatory Activity

    This article has 7 authors:
    1. Madison B. Adolph
    2. Atharv S. Garje
    3. Swati Balakrishnan
    4. Florian Morati
    5. Mauro Modesti
    6. Walter J. Chazin
    7. David Cortez

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  9. Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains

    This article has 4 authors:
    1. Kenrick A. Waite
    2. Gabrielle Vontz
    3. Stella Y. Lee
    4. Jeroen Roelofs

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  10. A Phosphoproteomics Data Resource for Systems-level Modeling of Kinase Signaling Networks

    This article has 10 authors:
    1. Song Feng
    2. James A. Sanford
    3. Thomas Weber
    4. Chelsea M. Hutchinson-Bunch
    5. Panshak P. Dakup
    6. Vanessa L. Paurus
    7. Kwame Attah
    8. Herbert M. Sauro
    9. Wei-Jun Qian
    10. H. Steven Wiley

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
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