Latest preprint reviews

1. Experience-dependent plasticity of a highly specific olfactory circuit in Drosophila melanogaster

   This article has 5 authors:

   1. Benjamin Fabian
   2. Veit Grabe
   3. Rolf G. Beutel
   4. Bill S. Hansson
   5. Silke Sachse

   Reviewed by preLights

2. A direct experimental test of Ohno’s hypothesis

   This article has 8 authors:

   1. Ljiljana Mihajlovic
   2. Bharat Ravi Iyengar
   3. Florian Baier
   4. Içvara Barbier
   5. Justyna Iwaszkiewicz
   6. Vincent Zoete
   7. Andreas Wagner
   8. Yolanda Schaerli

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This fundamental study uses a creative experimental system to directly test Ohno's hypothesis, which describes how and why new genes might evolve by duplication of existing ones. In agreement with existing criticism of Ohno's original idea, the authors present compelling evidence that having two gene copies does not speed up the evolution of a new function as posited by Ohno, but instead leads to the rapid inactivation of one of the copies through the accumulation of mostly deleterious mutations. These findings will be of broad interest to evolutionary biologists and geneticists.

   Reviewed by eLife, preLights

3. Characterization of Identified Dopaminergic Neurons in the Mouse Forebrain and Midbrain

   This article has 4 authors:

   1. Maggy Yu Hei Lau
   2. Sana Gadiwalla
   3. Susan Jones
   4. Elisa Galliano

   Reviewed by preLights

4. Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

   This article has 2 authors:

   1. Jayne Aiken
   2. Erika L. F. Holzbaur

   Reviewed by preLights

5. Inference of drug off-target effects on cellular signaling using interactome-based deep learning

   This article has 3 authors:

   1. Nikolaos Meimetis
   2. Douglas A. Lauffenburger
   3. Avlant Nilsson

   Reviewed by preLights

6. Hibernating ribosomes tether to mitochondria as an adaptive response to cellular stress during glucose depletion

   This article has 8 authors:

   1. Olivier Gemin
   2. Maciej Gluc
   3. Michael Purdy
   4. Higor Rosa
   5. Moritz Niemann
   6. Yelena Peskova
   7. Simone Mattei
   8. Ahmad Jomaa

   Reviewed by preLights

7. Structured RhoGEF recruitment drives myosin II organization on large exocytotic vesicles

   This article has 5 authors:

   1. Kumari Kamalesh
   2. Dagan Segal
   3. Ori Avinoam
   4. Eyal D. Schejter
   5. Ben-Zion Shilo

   Reviewed by preLights

8. The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

   This article has 12 authors:

   1. Hasan Mamar
   2. Roberta Fajka-Boja
   3. Mónika Mórocz
   4. Eva Pinto Jurado
   5. Siham Zentout
   6. Alexandra Mihuț
   7. Anna Georgina Kopasz
   8. Mihály Mérey
   9. Rebecca Smith
   10. Lajos Haracska
   11. Sébastien Huet
   12. Gyula Timinszky

   Reviewed by preLights

9. Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

   This article has 35 authors:

   1. Jeanette A.I. Johnson
   2. Genevieve L. Stein-O’Brien
   3. Max Booth
   4. Randy Heiland
   5. Furkan Kurtoglu
   6. Daniel R. Bergman
   7. Elmar Bucher
   8. Atul Deshpande
   9. André Forjaz
   10. Michael Getz
   11. Ines Godet
   12. Melissa Lyman
   13. John Metzcar
   14. Jacob Mitchell
   15. Andrew Raddatz
   16. Heber Rocha
   17. Jacobo Solorzano
   18. Aneequa Sundus
   19. Yafei Wang
   20. Danielle Gilkes
   21. Luciane T. Kagohara
   22. Ashley L. Kiemen
   23. Elizabeth D. Thompson
   24. Denis Wirtz
   25. Pei-Hsun Wu
   26. Neeha Zaidi
   27. Lei Zheng
   28. Jacquelyn W. Zimmerman
   29. Elizabeth M. Jaffee
   30. Young Hwan Chang
   31. Lisa M. Coussens
   32. Joe W. Gray
   33. Laura M. Heiser
   34. Elana J. Fertig
   35. Paul Macklin

   Reviewed by preLights

10. Effects of Aerobic Exercise in Hepatic Lipid Droplet-Mitochondria interaction in Non-alcoholic Fatty Liver Disease

    This article has 13 authors:

    1. Juan Carlos Bórquez
    2. Francisco Díaz-Castro
    3. Francisco Pino-de La Fuente
    4. Karla Espinoza
    5. Ana María Figueroa
    6. Inma Martínez-Ruíz
    7. Vanessa Hernández
    8. Iliana López-Soldado
    9. Raúl Ventura
    10. Alejandra Espinosa
    11. Víctor Cortés
    12. María Isabel Hernández-Alvarez
    13. Rodrigo Troncoso

    Reviewed by preLights