preLights

Latest preprint reviews

1. Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes

   This article has 6 authors:

   1. Aditi Kulkarni
   2. Wanqin Yu
   3. Alex Moon
   4. Ashmita Pandey
   5. Kathryn A. Hanley
   6. Jiannong Xu

   Reviewed by preLights

2. Remembering immunity: Neuronal ensembles in the insular cortex encode and retrieve specific immune responses

   This article has 15 authors:

   1. Tamar Koren
   2. Maria Krot
   3. Nadia T. Boshnak
   4. Mariam Amer
   5. Tamar Ben-Shaanan
   6. Hilla Azulay-Debby
   7. Haitham Hajjo
   8. Eden Avishai
   9. Maya Schiller
   10. Hedva Haykin
   11. Ben Korin
   12. Dorit Cohen-Farfara
   13. Fahed Hakim
   14. Kobi Rosenblum
   15. Asya Rolls

   Reviewed by preLights

3. Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization

   This article has 9 authors:

   1. Gil Kanfer
   2. Shireen A. Sarraf
   3. Yaakov Maman
   4. Heather Baldwin
   5. Kory R. Johnson
   6. Michael E. Ward
   7. Martin Kampmann
   8. Jennifer Lippincott-Schwartz
   9. Richard J. Youle

   Reviewed by preLights

4. Guide RNA categorization enables target site choice in Tn7-CRISPR-Cas transposons

   This article has 3 authors:

   1. Michael T. Petassi
   2. Shan-Chi Hsieh
   3. Joseph E. Peters

   Reviewed by preLights

5. From amazing work to I beg to differ - analysis of bioRxiv preprints that received one public comment till September 2019

   This article has 4 authors:

   1. Mario Malički
   2. Joseph Costello
   3. Juan Pablo Alperin
   4. Lauren A. Maggio

   Reviewed by preLights

6. A functional genetic toolbox for human tissue-derived organoids

   This article has 9 authors:

   1. Dawei Sun
   2. Lewis Evans
   3. Francesca Perrone
   4. Vanesa Sokleva
   5. Kyungtae Lim
   6. Saba Rezakhani
   7. Matthias Lutolf
   8. Matthias Zilbauer
   9. Emma L Rawlins

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     In this paper Sun and colleagues aimed to demonstrate the feasibility of using CRISPR-based gene editing techniques applied to tissue-derived human fetal lung organoids. While previous studies have used CRISPR-Cas9 to perform knock-in or knock-out studies in organoids (such as intestinal, hepatic or tumor organoids), this is the first report to apply these tools to a tissue-derived lung organoid model. A major strength of this report is the additional use of CRISPRi and CRISPRa technologies. The work is well done, clearly presented and makes an important contribution to the literature.

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #3 agreed to share their name with the authors.)

   Reviewed by eLife, preLights

7. Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains

   This article has 11 authors:

   1. Xiaoyu Sun
   2. Donovan Y.Z. Phua
   3. Lucas Axiotakis
   4. Mark A. Smith
   5. Elizabeth Blankman
   6. Rui Gong
   7. Robert C. Cail
   8. Santiago Espinosa de los Reyes
   9. Mary C. Beckerle
   10. Clare M. Waterman
   11. Gregory M. Alushin

   Reviewed by preLights

8. During hippocampal inactivation, grid cells maintain synchrony, even when the grid pattern is lost

   This article has 6 authors:

   1. Noam Almog
   2. Gilad Tocker
   3. Tora Bonnevie
   4. Edvard I Moser
   5. May-Britt Moser
   6. Dori Derdikman

   Reviewed by preLights

9. Antigenic variation by switching inter-chromosomal interactions with an RNA splicing locus in trypanosomes

   This article has 8 authors:

   1. Joana Faria
   2. Vanessa Luzak
   3. Laura S.M. Müller
   4. Benedikt G. Brink
   5. Sebastian Hutchinson
   6. Lucy Glover
   7. David Horn
   8. T. Nicolai Siegel

   Reviewed by preLights

10. Actomyosin forces and the energetics of red blood cell invasion by the malaria parasite Plasmodium falciparum

    This article has 3 authors:

    1. Thomas C. A. Blake
    2. Silvia Haase
    3. Jake Baum

    Reviewed by preLights