Pharmacology and Toxicology

Triphosphates of the Two Components in DESCOVY and TRUVADA are Inhibitors of the SARS-CoV-2 Polymerase

This article has 9 authors:
1. Steffen Jockusch
2. Chuanjuan Tao
3. Xiaoxu Li
4. Thomas K. Anderson
5. Minchen Chien
6. Shiv Kumar
7. James J. Russo
8. Robert N. Kirchdoerfer
9. Jingyue Ju
Reviewed by ScreenIT

This article has 1 evaluationAppears in 1 listLatest version Apr 5, 2020Latest activity Mar 1, 2021
Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and FlipGFP-based reporter assay

This article has 15 authors:
1. Zilei Xia
2. Michael Dominic Sacco
3. Chunlong Ma
4. Julia Alma Townsend
5. Naoya Kitamura
6. Yanmei Hu
7. Mandy Ba
8. Tommy Szeto
9. Xiujun Zhang
10. Xiangzhi Meng
11. Fushun Zhang
12. Yan Xiang
13. Michael Thomas Marty
14. Yu Chen
15. Jun Wang
Reviewed by ScreenIT

This article has 1 evaluationAppears in 1 listLatest version Mar 16, 2021Latest activity Mar 24, 2021
Identification of SARS-CoV-2 induced pathways reveal drug repurposing strategies

This article has 15 authors:
1. Namshik Han
2. Woochang Hwang
3. Konstantinos Tzelepis
4. Patrick Schmerer
5. Eliza Yankova
6. Méabh MacMahon
7. Winnie Lei
8. Nicholas M Katritsis
9. Anika Liu
10. Alison Schuldt
11. Rebecca Harris
12. Kathryn Chapman
13. Frank McCaughan
14. Friedemann Weber
15. Tony Kouzarides
Reviewed by ScreenIT

This article has 1 evaluationAppears in 1 listLatest version Aug 25, 2020Latest activity Mar 1, 2021
Tafenoquine inhibits replication of SARS-Cov-2 at pharmacologically relevant concentrations in vitro

This article has 6 authors:
1. Geoffrey S. Dow
2. Angela Luttick
3. Jen Fenner
4. David Wesche
5. Karen Rowland Yeo
6. Craig Rayner
Reviewed by ScreenIT

This article has 2 evaluationsAppears in 1 listLatest version Jul 12, 2020Latest activity Mar 1, 2021
In vitro screening of herbal medicinal products for their supportive curing potential in the context of SARS-CoV-2

This article has 5 authors:
1. Hoai Thi Thu Tran
2. Philipp Peterburs
3. Jan Seibel
4. D. Abramov-Sommariva
5. Evelyn Lamy
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This article has 1 evaluationAppears in 1 listLatest version Mar 1, 2021Latest activity Mar 15, 2021
Pharmacokinetics of Orally Administered GS-441524 in Dogs

This article has 13 authors:
1. Victoria C. Yan
2. Cong-Dat Pham
3. Matthew J. Yan
4. Alexander J. Yan
5. Sunada Khadka
6. Kenisha Arthur
7. Jeffrey J. Ackroyd
8. Dimitra K. Georgiou
9. Laura E. Roon
10. Lane R. Bushman
11. Peter L. Anderson
12. Chun Li
13. Florian L. Muller
Reviewed by ScreenIT

This article has 1 evaluationAppears in 1 listLatest version Feb 5, 2021Latest activity Mar 1, 2021
Ambroxol Hydrochloride Inhibits the Interaction between Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein’s Receptor Binding Domain and Recombinant Human ACE2

This article has 3 authors:
1. Omonike A. Olaleye
2. Manvir Kaur
3. Collins C. Onyenaka
Reviewed by ScreenIT

This article has 2 evaluationsAppears in 1 listLatest version Sep 14, 2020Latest activity Mar 1, 2021
Bromodomain and extraterminal protein inhibitor, apabetalone (RVX-208), reduces ACE2 expression and attenuates SARS-CoV-2 infection in vitro

This article has 12 authors:
1. Dean Gilham
2. Audrey L Smith
3. Li Fu
4. Dalia Y Moore
5. Abenaya Muralidharan
6. St. Patrick M Reid
7. Stephanie C Stotz
8. Jan O Johansson
9. Michael Sweeney
10. Norman CW Wong
11. Ewelina Kulikowski
12. Dalia El-Gamal
Reviewed by ScreenIT

This article has 1 evaluationAppears in 1 listLatest version Mar 11, 2021Latest activity Mar 15, 2021
Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction

This article has 16 authors:
1. Michele Biagioli
2. Silvia Marchianò
3. Rosalinda Roselli
4. Cristina Di Giorgio
5. Rachele Bellini
6. Martina Bordoni
7. Anna Gidari
8. Samuele Sabbatini
9. Daniela Francisci
10. Bianca Fiorillo
11. Bruno Catalanotti
12. Eleonora Distrutti
13. Adriana Carino
14. Angela Zampella
15. Gabriele Costantino
16. Stefano Fiorucci
Reviewed by ScreenIT

This article has 1 evaluationAppears in 1 listLatest version Jun 1, 2021Latest activity Mar 1, 2021
Stapled Peptides Based on Human Angiotensin-Converting Enzyme 2 (ACE2) Potently Inhibit SARS-CoV-2 Infection In Vitro

This article has 8 authors:
1. Francesca Curreli
2. Sofia M. B. Victor
3. Shahad Ahmed
4. Aleksandra Drelich
5. Xiaohe Tong
6. Chien-Te K. Tseng
7. Christopher D. Hillyer
8. Asim K. Debnath
Reviewed by ScreenIT

This article has 1 evaluationAppears in 1 listLatest version Dec 22, 2020Latest activity Mar 1, 2021

Previous Page 19 of 23 Next

Pharmacology and Toxicology

Triphosphates of the Two Components in DESCOVY and TRUVADA are Inhibitors of the SARS-CoV-2 Polymerase

Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and FlipGFP-based reporter assay

Identification of SARS-CoV-2 induced pathways reveal drug repurposing strategies

Tafenoquine inhibits replication of SARS-Cov-2 at pharmacologically relevant concentrations in vitro

In vitro screening of herbal medicinal products for their supportive curing potential in the context of SARS-CoV-2

Pharmacokinetics of Orally Administered GS-441524 in Dogs

Ambroxol Hydrochloride Inhibits the Interaction between Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein’s Receptor Binding Domain and Recombinant Human ACE2

Bromodomain and extraterminal protein inhibitor, apabetalone (RVX-208), reduces ACE2 expression and attenuates SARS-CoV-2 infection in vitro

Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction

Stapled Peptides Based on Human Angiotensin-Converting Enzyme 2 (ACE2) Potently Inhibit SARS-CoV-2 Infection In Vitro