Pharmacology and Toxicology

  1. KLF2 is a therapeutic target for COVID-19 induced endothelial dysfunction

    1. Suowen Xu
    2. Sihui Luo
    3. Xueying Zheng
    4. Jianping Weng

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2

    1. Tia A. Tummino
    2. Veronica V. Rezelj
    3. Benoit Fischer
    4. Audrey Fischer
    5. Matthew J. O’Meara
    6. Blandine Monel
    7. Thomas Vallet
    8. Ziyang Zhang
    9. Assaf Alon
    10. Henry R. O’Donnell
    11. Jiankun Lyu
    12. Heiko Schadt
    13. Kris M White
    14. Nevan J. Krogan
    15. Laszlo Urban
    16. Kevan M. Shokat
    17. Andrew C. Kruse
    18. Adolfo García-Sastre
    19. Olivier Schwartz
    20. Francesca Moretti
    21. Marco Vignuzzi
    22. Francois Pognan
    23. Brian K. Shoichet

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Human ACE2 peptide mimics block SARS-CoV-2 Pulmonary Cells Infection

    1. Philippe Karoyan
    2. Vincent Vieillard
    3. Estelle Odile
    4. Alexis Denis
    5. Amélie Guihot
    6. Charles-Edouard Luyt
    7. Luis Gómez-Morales
    8. Pascal Grondin
    9. Olivier Lequin

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2

    1. Kaleb B. Tsegay
    2. Christiana M. Adeyemi
    3. Edward P. Gniffke
    4. D. Noah Sather
    5. John K. Walker
    6. Stephen E. P. Smith

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Triphosphates of the Two Components in DESCOVY and TRUVADA are Inhibitors of the SARS-CoV-2 Polymerase

    1. Steffen Jockusch
    2. Chuanjuan Tao
    3. Xiaoxu Li
    4. Thomas K. Anderson
    5. Minchen Chien
    6. Shiv Kumar
    7. James J. Russo
    8. Robert N. Kirchdoerfer
    9. Jingyue Ju

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay

    1. Chunlong Ma
    2. Michael Dominic Sacco
    3. Zilei Xia
    4. George Lambrinidis
    5. Julia Alma Townsend
    6. Yanmei Hu
    7. Xiangzhi Meng
    8. Tommy Szeto
    9. Mandy Ba
    10. Xiujun Zhang
    11. Maura Gongora
    12. Fushun Zhang
    13. Michael Thomas Marty
    14. Yan Xiang
    15. Antonios Kolocouris
    16. Yu Chen
    17. Jun Wang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Identification of SARS-CoV-2–induced pathways reveals drug repurposing strategies

    1. Namshik Han
    2. Woochang Hwang
    3. Konstantinos Tzelepis
    4. Patrick Schmerer
    5. Eliza Yankova
    6. Méabh MacMahon
    7. Winnie Lei
    8. Nicholas M. Katritsis
    9. Anika Liu
    10. Ulrike Felgenhauer
    11. Alison Schuldt
    12. Rebecca Harris
    13. Kathryn Chapman
    14. Frank McCaughan
    15. Friedemann Weber
    16. Tony Kouzarides

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Tafenoquine inhibits replication of SARS-Cov-2 at pharmacologically relevant concentrations in vitro

    1. Geoffrey S. Dow
    2. Angela Luttick
    3. Jen Fenner
    4. David Wesche
    5. Karen Rowland Yeo
    6. Craig Rayner

    Reviewed by ScreenIT

    2 evaluationsAppears in 1 listLatest version Latest activity

  9. In vitro screening of herbal medicinal products for their supportive curing potential in the context of SARS-CoV-2

    1. Hoai Thi Thu Tran
    2. Philipp Peterburs
    3. Jan Seibel
    4. D. Abramov-Sommariva
    5. Evelyn Lamy

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Pharmacokinetics of Orally Administered GS-441524 in Dogs

    1. Victoria C. Yan
    2. Cong-Dat Pham
    3. Matthew J. Yan
    4. Alexander J. Yan
    5. Sunada Khadka
    6. Kenisha Arthur
    7. Jeffrey J. Ackroyd
    8. Dimitra K. Georgiou
    9. Laura E. Roon
    10. Lane R. Bushman
    11. Peter L. Anderson
    12. Chun Li
    13. Florian L. Muller

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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