Pharmacology and Therapeutics

  1. Efficacy of Tocilizumab in Covid 19: A metanalysis of case series studies

    1. Shalam Mohamed Hussain
    2. Ayesha Farhana Syeda
    3. Osama Al-Wutayd
    4. Abdullah Al Nafeesah
    5. Mohammad Alshammari
    6. Sulaiman Alnasser
    7. Nandakumar Krishnadas

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Telmisartan for treatment of Covid-19 patients: An open multicenter randomized clinical trial

    1. Mariano Duarte
    2. Facundo Pelorosso
    3. Liliana N. Nicolosi
    4. M. Victoria Salgado
    5. Héctor Vetulli
    6. Analía Aquieri
    7. Francisco Azzato
    8. Marcela Castro
    9. Javier Coyle
    10. Ignacio Davolos
    11. Ignacio Fernandez Criado
    12. Rosana Gregori
    13. Pedro Mastrodonato
    14. María C. Rubio
    15. Sergio Sarquis
    16. Fernando Wahlmann
    17. Rodolfo P. Rothlin

    Reviewed by ScreenIT

    2 evaluationsAppears in 1 listLatest version Latest activity

  3. May we overcome the current serious limitations for distributing reconstituted mRNA vaccines?

    1. Santiago Grau
    2. Olivia Ferrández
    3. Elena Martín-García
    4. Rafael Maldonado

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance

    1. Mohd Anisul
    2. Jarrod Shilts
    3. Jeremy Schwartzentruber
    4. James Hayhurst
    5. Annalisa Buniello
    6. Elmutaz Shaikho Elhaj Mohammed
    7. Jie Zheng
    8. Michael Holmes
    9. David Ochoa
    10. Miguel Carmona
    11. Joseph Maranville
    12. Tom R Gaunt
    13. Valur Emilsson
    14. Vilmundur Gudnason
    15. Ellen M McDonagh
    16. Gavin J Wright
    17. Maya Ghoussaini
    18. Ian Dunham

    • Curated by eLife

      Evaluation Summary:

      This study analyzes publicly available genomic and proteomic data to identify host proteins that may be involved in regulation of COVID-19 susceptibility and severity. Several known and new targets are identified, further revealing the complexity of host genetic variation in COVID-19 disease.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife, ScreenIT

    4 evaluationsAppears in 2 listsLatest version Latest activity

  5. Tocilizumab and Mortality in Hospitalised Patients with Covid-19. A Systematic Review Comparing Randomised Trials with Observational Studies

    1. Nawab Qizilbash
    2. Bélène Podmore
    3. Alessandra Lacetera
    4. Itziar Ubillos
    5. Kirsty Andresen
    6. Ana Roncero Martín
    7. Jara Majuelos-Melguizo
    8. Ana Cuñado Moral
    9. Marina Hinojosa Campos
    10. Jeffrey K Aronson
    11. Stuart Pocock

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. CERC-002, a human anti-LIGHT mAb reduces respiratory failure and death in hospitalized COVID-19 ARDS patients

    1. David S. Perlin
    2. Garry A. Neil
    3. Colleen Anderson
    4. Inbal Zafir-Lavie
    5. Lori Roadcap
    6. Shane Raines
    7. Carl F. Ware
    8. H. Jeffrey Wilkins

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Concentration-dependent mortality of chloroquine in overdose

    1. James A Watson
    2. Joel Tarning
    3. Richard M Hoglund
    4. Frederic J Baud
    5. Bruno Megarbane
    6. Jean-Luc Clemessy
    7. Nicholas J White

    Reviewed by ScreenIT, eLife

    2 evaluationsAppears in 2 listsLatest version Latest activity
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