Immunology

Possible Cross-Reactivity of Feline and White-Tailed Deer Antibodies against the SARS-CoV-2 Receptor Binding Domain

1. Trevor J. Hancock
2. Peyton Hickman
3. Niloo Kazerooni
4. Melissa Kennedy
5. Stephen A. Kania
6. Michelle Dennis
7. Nicole Szafranski
8. Richard Gerhold
9. Chunlei Su
10. Tom Masi
11. Stephen Smith
12. Tim E. Sparer

Reviewed by ScreenIT

Modeling and predicting the overlap of B- and T-cell receptor repertoires in healthy and SARS-CoV-2 infected individuals

1. Maria Ruiz Ortega
2. Natanael Spisak
3. Thierry Mora
4. Aleksandra M. Walczak

• Curated by eLife

  Evaluation Summary:

  This work is potentially very important to dissect the immune repertoire of T/B cells, which is one of the most critical/difficult parts for the adaptive immune system to achieve antigen specificity. These conclusions and proposed methods will require additional experimental support and further validation in different disease conditions.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

Reviewed by eLife, ScreenIT

Disrupted Peyer’s Patch Microanatomy in COVID-19 Including Germinal Centre Atrophy Independent of Local Virus

1. Silvia C. Trevelin
2. Suzanne Pickering
3. Katrina Todd
4. Cynthia Bishop
5. Michael Pitcher
6. Jose Garrido Mesa
7. Lucia Montorsi
8. Filomena Spada
9. Nedyalko Petrov
10. Anna Green
11. Manu Shankar-Hari
12. Stuart J.D. Neil
13. Jo Spencer

Reviewed by ScreenIT

Variable loss of antibody potency against SARS-CoV-2 B.1.1.529 (Omicron)

1. Daniel J. Sheward
2. Changil Kim
3. Roy A. Ehling
4. Alec Pankow
5. Xaquin Castro Dopico
6. Darren Martin
7. Sai Reddy
8. Joakim Dillner
9. Gunilla B. Karlsson Hedestam
10. Jan Albert
11. Ben Murrell

Reviewed by ScreenIT

ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection

1. Krystal L. Ching
2. Maren de Vries
3. Juan Gago
4. Kristen Dancel-Manning
5. Joseph Sall
6. William J. Rice
7. Clea Barnett
8. Alireza Khodadadi-Jamayran
9. Aristotelis Tsirigos
10. Feng-Xia Liang
11. Lorna E. Thorpe
12. Bo Shopsin
13. Leopoldo N. Segal
14. Meike Dittmann
15. Victor J. Torres
16. Ken Cadwell

Reviewed by ScreenIT

Neutrophil profiles of pediatric COVID-19 and multisystem inflammatory syndrome in children

1. Brittany P. Boribong
2. Thomas J. LaSalle
3. Yannic C. Bartsch
4. Felix Ellett
5. Maggie E. Loiselle
6. Jameson P. Davis
7. Anna L.K. Gonye
8. David B. Sykes
9. Soroush Hajizadeh
10. Johannes Kreuzer
11. Shiv Pillai
12. Wilhelm Haas
13. Andrea G. Edlow
14. Alessio Fasano
15. Galit Alter
16. Daniel Irimia
17. Moshe Sade-Feldman
18. Lael M. Yonker

Reviewed by ScreenIT

A third vaccination with a single T cell epitope protects against SARS-CoV-2 infection in the absence of neutralizing antibodies

1. Iris N. Pardieck
2. Esmé T.I. van der Gracht
3. Dominique M.B. Veerkamp
4. Felix M. Behr
5. Suzanne van Duikeren
6. Guillaume Beyrend
7. Jasper Rip
8. Reza Nadafi
9. Tetje C. van der Sluis
10. Elham Beyranvand Nejad
11. Nils Mülling
12. Dena J. Brasem
13. Marcel G.M. Camps
14. Sebenzile K. Myeni
15. Peter J. Bredenbeek
16. Marjolein Kikkert
17. Yeonsu Kim
18. Luka Cicin-Sain
19. Tamim Abdelaal
20. Klaas P.J.M. van Gisbergen
21. Kees L.M.C. Franken
22. Jan Wouter Drijfhout
23. Cornelius J.M. Melief
24. Gerben C.M. Zondag
25. Ferry Ossendorp
26. Ramon Arens

Reviewed by ScreenIT

A recurring YYDRxG pattern in broadly neutralizing antibodies to a conserved site on SARS-CoV-2, variants of concern, and related viruses

1. Hejun Liu
2. Chengzi I. Kaku
3. Ge Song
4. Meng Yuan
5. Raiees Andrabi
6. Dennis R. Burton
7. Laura M. Walker
8. Ian A. Wilson

Reviewed by ScreenIT

Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms

1. Xin Wang
2. Anjun Jiao
3. Lina Sun
4. Wenhua Li
5. Biao Yang
6. Yanhong Su
7. Renyi Ding
8. Cangang Zhang
9. Haiyan Liu
10. Xiaofeng Yang
11. Chenming Sun
12. Baojun Zhang

• Curated by eLife

  Evaluation Summary:

  The authors have discovered that the transcription factor Zfp335 is an important regulator of early T cell development in the thymus. This paper will be of interest to scientists within the field of T cell development. The approaches used are thoughtful and rigorous and the key claims are supported by the data. Whether or not Zfp335 specifically controls beta-selection via the gene targets described requires additional experimentation.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife

Distinguishing COVID-19 infection and vaccination history by T cell reactivity

1. Esther Dawen Yu
2. Eric Wang
3. Emily Garrigan
4. Benjamin Goodwin
5. Aaron Sutherland
6. James Chang
7. Rosa Isela Gálvez
8. Jose Mateus
9. Stephen A. Rawlings
10. Davey M. Smith
11. April Frazier
12. Daniela Weiskopf
13. Jennifer M. Dan
14. Shane Crotty
15. Alba Grifoni
16. Ricardo da Silva Antunes
17. Alessandro Sette

Reviewed by ScreenIT