Hematology

Morphology-based classification of sickle cell disease and β-thalassemia using a low-cost automated microscope and machine learning

1. Pranav Shrestha
2. Hendrik Lohse
3. Christopher Bhatla
4. Heather McCartney
5. Alaa Alzaki
6. Navdeep Sandhu
7. Pradip Kumar Oli
8. Hongquan Li
9. Manu Prakash
10. Ali Amid
11. Rodrigo Onell
12. Nicholas Au
13. Hayley Merkeley
14. Videsh Kapoor
15. Rajan Pande
16. Boris Stoeber

Reviewed by Arcadia Science

Tumor purity-related genes for predicting the prognosis and drug sensitivity of DLBCL patients

1. Zhenbang Ye
2. Ning Huang
3. Yongliang Fu
4. Rongle Tian
5. Liming Wang
6. Wenting Huang

• Curated by eLife

  eLife assessment

  This study presents a predictive scoring system in DLBCL based on the expression of three tumour microenvironment-related genes. Such a scoring system seems useful for predicting tumour purity levels in DLBCL. The provided evidence showing an association between worse DLBLC prognosis and high-risk score is solid, but it is incomplete to draw a clear conclusion about the links between risk score and drug sensitivity.

Reviewed by eLife

Primaquine in glucose-6-phosphate dehydrogenase deficiency: an adaptive pharmacometric assessment of ascending dose regimens in healthy volunteers

1. Sasithon Pukrittayakamee
2. Podjanee Jittamala
3. James A Watson
4. Borimas Hanboonkunupakarn
5. Pawanrat Leungsinsiri
6. Kittiyod Poovorawan
7. Kesinee Chotivanich
8. Germana Bancone
9. Cindy S Chu
10. Mallika Imwong
11. Nicholas PJ Day
12. Walter RJ Taylor
13. Nicholas J White

• Curated by eLife

  eLife assessment

  This manuscript addresses an important question, that in countries endemic for P vivax the need to administer a primaquine (PQ) course adequate to prevent relapse in G6PD deficient persons poses a real dilemma. On one hand PQ will cause haemolysis; on the other hand, without PQ the chance of relapse is very high. As a result, out of fear of severe haemolysis, PQ has been under-used. This manuscript is convincing that regimen (1) can be used successfully to deliver within 3 weeks, under hospital conditions, the dose of PQ required to prevent P vivax relapse.

Reviewed by eLife

Dynamics of coagulopathy in patients with different COVID-19 severity

1. Anna Kalinskaya
2. Oleg Dukhin
3. Ivan Molodtsov
4. Alexandra Maltseva
5. Denis Sokorev
6. Antonina Elizarova
7. Olga Sapozhnikova
8. Ksenia Glebova
9. Daria Stonogina
10. Soslan Shakhidzhanov
11. Evgeniy Nikonov
12. Alexey Mazus
13. Ilia Spiridonov
14. Fazly Ataullakhanov
15. Leonid Margolis
16. Alexander Shpektor
17. Elena Vasilieva

Reviewed by ScreenIT

Multiple myeloma and SARS-CoV-2 infection: clinical characteristics and prognostic factors of inpatient mortality

1. Joaquín Martínez-López
2. María-Victoria Mateos
3. Cristina Encinas
4. Anna Sureda
5. José Ángel Hernández-Rivas
6. Ana Lopez de la Guía
7. Diego Conde
8. Isabel Krsnik
9. Elena Prieto
10. Rosalía Riaza Grau
11. Mercedes Gironella
12. María Jesús Blanchard
13. Nerea Caminos
14. Carlos Fernández de Larrea
15. María Alicia Senin
16. Fernando Escalante
17. José Enrique de la Puerta
18. Eugenio Giménez
19. Pilar Martínez-Barranco
20. Juan José Mateos
21. Luis Felipe Casado
22. Joan Bladé
23. Juan José Lahuerta
24. Javier de la Cruz
25. Jesús San-Miguel

Reviewed by ScreenIT

Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients

1. Tiffany Thomas
2. Davide Stefanoni
3. Monika Dzieciatkowska
4. Aaron Issaian
5. Travis Nemkov
6. Ryan C. Hill
7. Richard O. Francis
8. Krystalyn E. Hudson
9. Paul W. Buehler
10. James C. Zimring
11. Eldad A. Hod
12. Kirk C. Hansen
13. Steven L. Spitalnik
14. Angelo D’Alessandro

Reviewed by ScreenIT

Data from COVID-19 Infections and Clinical Outcomes in Patients with Multiple Myeloma in New York City: A Cohort Study from Five Academic Centers

1. Malin Hultcrantz
2. Joshua Richter
3. Cara A. Rosenbaum
4. Dhwani Patel
5. Eric L. Smith
6. Neha Korde
7. Sydney X. Lu
8. Sham Mailankody
9. Urvi A. Shah
10. Alexander M. Lesokhin
11. Hani Hassoun
12. Carlyn Tan
13. Francesco Maura
14. Andriy Derkach
15. Benjamin Diamond
16. Adriana Rossi
17. Roger N. Pearse
18. Deepu Madduri
19. Ajai Chari
20. David Kaminetzky
21. Marc J. Braunstein
22. Christian Gordillo
23. Ran Reshef
24. Ying Taur
25. Faith E. Davies
26. Sundar Jagannath
27. Ruben Niesvizky
28. Suzanne Lentzsch
29. Gareth J. Morgan
30. Ola Landgren

Reviewed by ScreenIT

Correlation of Coagulation Parameters With Clinical Outcomes During the Coronavirus-19 Surge in New York: Observational Cohort

1. Morayma Reyes Gil
2. Jesus D. Gonzalez-Lugo
3. Shafia Rahman
4. Mohammad Barouqa
5. James Szymanski
6. Kenji Ikemura
7. Yungtai Lo
8. Henny H. Billett

Reviewed by ScreenIT

Delayed‐phase thrombocytopenia in patients with coronavirus disease 2019 (COVID‐19)

1. Wanxin Chen
2. Ziping Li
3. Bohan Yang
4. Ping Wang
5. Qiong Zhou
6. Zhiguo Zhang
7. Jianhua Zhu
8. Xuexing Chen
9. Peng Yang
10. Hao Zhou

Reviewed by ScreenIT

The first report of the prevalence of COVID-19 in Chronic myelogenous leukemia patients in the core epidemic area of China: multicentre, cross-sectional survey

1. Dan-Yu Wang
2. Jing-Ming Guo
3. Zhuang-Zhi Yang
4. Guo-Lin Yuan
5. Li Meng
6. Wei-Ming Li

Reviewed by ScreenIT