Genomics

  1. Comparative Genomic Analyses Reveal a Specific Mutation Pattern Between Human Coronavirus SARS-CoV-2 and Bat-CoV RaTG13

    1. Longxian Lv
    2. Gaolei Li
    3. Jinhui Chen
    4. Xinle Liang
    5. Yudong Li

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Functional Pangenome Analysis Shows Key Features of E Protein Are Preserved in SARS and SARS-CoV-2

    1. Intikhab Alam
    2. Allan A. Kamau
    3. Maxat Kulmanov
    4. Łukasz Jaremko
    5. Stefan T. Arold
    6. Arnab Pain
    7. Takashi Gojobori
    8. Carlos M. Duarte

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Single-cell analysis of angiotensin-converting enzyme II expression in human kidneys and bladders reveals a potential route of 2019 novel coronavirus infection

    1. Wei Lin
    2. Jue Fan
    3. Long-Fei Hu
    4. Yan Zhang
    5. Joshua D. Ooi
    6. Ting Meng
    7. Peng Jin
    8. Xiang Ding
    9. Long-Kai Peng
    10. Lei Song
    11. Rong Tang
    12. Zhou Xiao
    13. Xiang Ao
    14. Xiang-Cheng Xiao
    15. Qiao-Ling Zhou
    16. Ping Xiao
    17. Yong Zhong

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Exploring the coronavirus pandemic with the WashU Virus Genome Browser

    1. Jennifer A. Flynn
    2. Deepak Purushotham
    3. Mayank N. K. Choudhary
    4. Xiaoyu Zhuo
    5. Changxu Fan
    6. Gavriel Matt
    7. Daofeng Li
    8. Ting Wang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Specific ACE2 Expression in Cholangiocytes May Cause Liver Damage After 2019-nCoV Infection

    1. Xiaoqiang Chai
    2. Longfei Hu
    3. Yan Zhang
    4. Weiyu Han
    5. Zhou Lu
    6. Aiwu Ke
    7. Jian Zhou
    8. Guoming Shi
    9. Nan Fang
    10. Jia Fan
    11. Jiabin Cai
    12. Jue Fan
    13. Fei Lan

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Alternative paths to immune activation: the role of costimulatory risk genes for polygenic inflammatory disease in T helper cells

    1. Alexandru-Ioan Voda
    2. Kristina Correa
    3. Jonathan Hamp
    4. Chloe Moscrop
    5. Michael Dustin
    6. Luke Jostins-Dean

    • Curated by eLife

      eLife assessment

      This valuable study examines the effects of different co-stimulatory pathways on gene expression and chromatin accessibility in T cells, in order to link the role of co-stimulatory proteins to genetic variants associated with inflammatory bowl disease (IBD). The work provides valuable insight into the role of alternative co-stimulatory proteins in controlling T cell responses. However, the data presented and the analyses performed are still incomplete and inconclusive with regards to IBD risk factors.

    Reviewed by eLife

    3 evaluationsAppears in 1 listLatest version Latest activity

  7. Identification of a non-canonical ciliate nuclear genetic code where UAA and UAG code for different amino acids

    1. Jamie McGowan
    2. Estelle S. Kilias
    3. Elisabet Alacid
    4. James Lipscombe
    5. Benjamin H. Jenkins
    6. Karim Gharbi
    7. Gemy G. Kaithakottil
    8. Iain C. Macaulay
    9. Seanna McTaggart
    10. Sally D. Warring
    11. Thomas A. Richards
    12. Neil Hall
    13. David Swarbreck

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity

  8. Massive genome reduction predates the divergence of Symbiodiniaceae dinoflagellates

    1. Sarah Shah
    2. Katherine E Dougan
    3. Yibi Chen
    4. Rosalyn Lo
    5. Gemma Laird
    6. Michael D A Fortuin
    7. Subash K Rai
    8. Valentine Murigneux
    9. Anthony J Bellantuono
    10. Mauricio Rodriguez-Lanetty
    11. Debashish Bhattacharya
    12. Cheong Xin Chan

    Reviewed by Arcadia Science

    6 evaluationsAppears in 1 listLatest version Latest activity

  9. The Crown Pearl V2: an improved genome assembly of the European freshwater pearl mussel Margaritifera margaritifera (Linnaeus, 1758)

    1. André Gomes-dos-Santos
    2. Manuel Lopes-Lima
    3. André M. Machado
    4. Thomas Forest
    5. Guillaume Achaz
    6. Amílcar Teixeira
    7. Vincent Prié
    8. L. Filipe C. Castro
    9. Elsa Froufe

    • Curated by GigaByte

      Editor’s Assessment

      Like other mollusc species, the freshwater pearl mussel (Margaritifera margaritifera) has a challenging genome to assemble owing to the large size of their genomes, heterozygosity, and repetitive sequence. The first published M. margaritifera genome was highly fragmented, but here an improved reference genome assembly was generated using PacBio CLR long reads to reduce fragmentation levels, missing and truncated genes, and chimerically assembled regions. The number of gene models predicted is a bit higher compared than other molluscan genomes, but after clarification and double checking these seem in line with some Mollusca and Bivalvia with similar and higher numbers of gene predictions. This new genome represents a new resource to start exploring the many biological, ecological, and evolutionary features of this threatened and commercially important group of organisms.

      This assessment refers to version 1 of this preprint.

    Reviewed by GigaByte

    2 evaluationsAppears in 2 listsLatest version Latest activity

  10. Annotating Metagenomically Assembled Bacteriophage from a Unique Ecological System using Protein Structure Prediction and Structure Homology Search

    1. Henry Say
    2. Ben Joris
    3. Daniel Giguere
    4. Gregory B. Gloor

    Reviewed by Arcadia Science

    17 evaluationsAppears in 1 listLatest version Latest activity
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