1. Evaluation of Clonal Hematopoiesis and Mosaic Loss of Y Chromosome in Cardiovascular Risk: an analysis in prospective studies

    This article has 15 authors:
    1. Sami Fawaz
    2. Severine Marti
    3. Melody Dufossée
    4. Yann Pucheu
    5. Astrid Gaufroy
    6. Jean Broitman
    7. Audrey Bidet
    8. Aicha Soumaré
    9. Gaelle Munsch
    10. Christophe Tzourio
    11. Stephanie Debette
    12. David-Alexandre Trégouët
    13. Chloe James
    14. Olivier Mansier
    15. Thierry Couffinhal
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      In this small study involving patients with a history of myocardial infarction, Fawaz et al. found no significant contribution of clonal hematopoiesis and mosaic loss of the Y chromosome to the incidence of myocardial infarction and atherosclerosis. Although the evidence provided by the study is incomplete due to its small sample size, the findings are valuable for guiding future larger studies that will further investigate this significant and controversial subject.

    Reviewed by eLife

    This article has 6 evaluationsAppears in 1 listLatest version Latest activity
  2. The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: a safety study

    This article has 14 authors:
    1. Gansheng Tan
    2. Anna L. Huguenard
    3. Kara M. Donovan
    4. Phillip Demarest
    5. Xiaoxuan Liu
    6. Ziwei Li
    7. Markus Adamek
    8. Kory Lavine
    9. Ananth K. Vellimana
    10. Terrance T. Kummer
    11. Joshua W. Osbun
    12. Gregory J. Zipfel
    13. Peter Brunner
    14. Eric C. Leuthardt
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study evaluated the role of transcutaneous auricular vagal nerve stimulation (taVNS) in patients with subarachnoid hemorrhage (SAH) randomized to taVNS vs sham, finding that those with active taVNS exhibited increased parasympathetic activity. The findings are important and cross-disciplinary, while the level of evidence is solid.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  3. Associations of age at diagnosis of breast cancer with incident myocardial infarction and heart failure: A prospective cohort study

    This article has 7 authors:
    1. Jie Liang
    2. Yang Pan
    3. Wenya Zhang
    4. Darui Gao
    5. Yongqian Wang
    6. Wuxiang Xie
    7. Fanfan Zheng
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      In this valuable study, the authors sought to investigate the associations of age at breast cancer onset with the incidence of myocardial infarction and heart failure. Based on results from a series of compelling statistical analyses, the authors conclude that a younger onset age of breast cancer is associated with myocardial infarction and heart failure, highlighting the need to carefully monitor the cardiovascular status of women who have been diagnosed with breast cancer.

    Reviewed by eLife

    This article has 6 evaluationsAppears in 1 listLatest version Latest activity
  4. Derivation and Internal Validation of Prediction Models for Pulmonary Hypertension Risk Assessment in a Cohort Inhabiting Tibet, China

    This article has 10 authors:
    1. Junhui Tang
    2. Rui Yang
    3. Hui Li
    4. Xiaodong Wei
    5. Zhen Yang
    6. Wenbin Cai
    7. Yao Jiang
    8. Ga Zhuo
    9. Li Meng
    10. Yali Xu
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study retrospectively analyzed clinical data to develop a risk prediction model for pulmonary hypertension in high-altitude populations. The evidence is solid and the findings are useful and hold clinical significance as the model can be used for intuitive and individualized prediction of pulmonary hypertension risk in these populations.

    Reviewed by eLife

    This article has 2 evaluationsAppears in 1 listLatest version Latest activity
  5. Identification of EPHB4 variants in dilated cardiomyopathy patients

    This article has 9 authors:
    1. Guillermo Luxán
    2. Marion Muhly-Reinholz
    3. Simone F. Glaser
    4. Johannes Trebing
    5. Christoph Reich
    6. Jan Haas
    7. Farbod Sedaghat-Hamedani
    8. Benjamin Meder
    9. Stefanie Dimmeler

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  6. Predicting ventricular tachycardia circuits in patients with arrhythmogenic right ventricular cardiomyopathy using genotype-specific heart digital twins

    This article has 12 authors:
    1. Yingnan Zhang
    2. Kelly Zhang
    3. Adityo Prakosa
    4. Cynthia James
    5. Stefan L Zimmerman
    6. Richard Carrick
    7. Eric Sung
    8. Alessio Gasperetti
    9. Crystal Tichnell
    10. Brittney Murray
    11. Hugh Calkins
    12. Natalia A Trayanova
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This important study brings together a clear application of the digital twin approach to make predictions using patient specific models with different genotypes. The data are compelling and go beyond the current state-of-the-art to support proof-of-principle evidence. Given the low subject numbers, further studies will be required going forward to support the veracity of the data and its translational utility.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
  7. Early Diagnosis and Clinical Significance of Acute Cardiac Injury - Under the Iceberg: A Retrospective Cohort Study of 619 Non-critically Ill Hospitalized COVID-19 Pneumonia Patients

    This article has 10 authors:
    1. Yang Xie
    2. Sichun Chen
    3. Xueli Wang
    4. Baige Li
    5. Tianlu Zhang
    6. Xingwei He
    7. Ningling Sun
    8. Luyan Wang
    9. Hesong Zeng
    10. Yin Shen

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  8. Impact of congestive heart failure and role of cardiac biomarkers in COVID-19 patients: A systematic review and meta-analysis

    This article has 9 authors:
    1. Tarun Dalia
    2. Shubham Lahan
    3. Sagar Ranka
    4. Prakash Acharya
    5. Archana Gautam
    6. Amandeep Goyal
    7. Ioannis Mastoris
    8. Andrew Sauer
    9. Zubair Shah

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  9. Excess of cardiovascular deaths during the COVID-19 pandemic in Brazilian capital cities

    This article has 7 authors:
    1. Luisa Campos Caldeira Brant
    2. Bruno Ramos Nascimento
    3. Renato Azeredo Teixeira
    4. Marcelo Antônio Cartaxo Queiroga Lopes
    5. Deborah Carvalho Malta
    6. Glaucia Maria Moraes Oliveira
    7. Antonio Luiz Pinho Ribeiro

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  10. Chloroquine, but not hydroxychlorquine, prolongs the QT interval in a primary care population

    This article has 6 authors:
    1. Jonas L. Isaksen
    2. Anders G. Holst
    3. Adrian Pietersen
    4. Jonas B. Nielsen
    5. Claus Graff
    6. Jørgen K. Kanters

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
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