1. Associations of age at diagnosis of breast cancer with incident myocardial infarction and heart failure: a prospective cohort study

    This article has 7 authors:
    1. Jie Liang
    2. Yang Pan
    3. Wenya Zhang
    4. Darui Gao
    5. Yongqian Wang
    6. Wuxiang Xie
    7. Fanfan Zheng
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      In this valuable study, the authors sought to investigate the associations of age at breast cancer onset with the incidence of myocardial infarction and heart failure. Based on results from a series of solid statistical analyses, the authors conclude that a younger onset age of breast cancer is associated with myocardial infarction and heart failure, highlighting the need to carefully monitor the cardiovascular status of women who have been diagnosed with breast cancer.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
  2. Comprehensive Evaluation of Clonal Hematopoiesis and Mosaic Loss of Y Chromosome in Cardiovascular Risk: A Thorough Analysis in prospective studies

    This article has 15 authors:
    1. S Fawaz
    2. S Marti
    3. M Dufossée
    4. Y Pucheu
    5. A Gaufroy
    6. J Broitman
    7. A Bidet
    8. A Soumaré
    9. G Munsch
    10. C Tzourio
    11. S Debette
    12. DA Trégouët
    13. C James
    14. O Mansier
    15. T Couffinhal
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      In this small-scale study, Fawaz et al. report a significant prevalence of somatic mutations such as Clonal Hematopoiesis of Indeterminate Potential (CHIP) and mosaic loss of Y chromosome (mLOY), but lack of their association with a history of myocardial infarction (MI). The study utilized sensitive techniques, including targeted high-throughput sequencing and digital PCR. The valuable findings by the authors present a contrast to earlier reports, yet they align somewhat with some studies that have demonstrated little or no link between clonal hematopoiesis and atherothrombotic events. Although the study offers convincing results, its limited sample size and brief follow-up period preclude drawing definitive conclusions.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
  3. Identification of EPHB4 variants in dilated cardiomyopathy patients

    This article has 9 authors:
    1. Guillermo Luxán
    2. Marion Muhly-Reinholz
    3. Simone F. Glaser
    4. Johannes Trebing
    5. Christoph Reich
    6. Jan Haas
    7. Farbod Sedaghat-Hamedani
    8. Benjamin Meder
    9. Stefanie Dimmeler

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  4. Predicting ventricular tachycardia circuits in patients with arrhythmogenic right ventricular cardiomyopathy using genotype-specific heart digital twins

    This article has 12 authors:
    1. Yingnan Zhang
    2. Kelly Zhang
    3. Adityo Prakosa
    4. Cynthia James
    5. Stefan L Zimmerman
    6. Richard Carrick
    7. Eric Sung
    8. Alessio Gasperetti
    9. Crystal Tichnell
    10. Brittney Murray
    11. Hugh Calkins
    12. Natalia A Trayanova
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This important study brings together a clear application of the digital twin approach to make predictions using patient specific models with different genotypes. The data are compelling and go beyond the current state-of-the-art to support proof-of-principle evidence. Given the low subject numbers, further studies will be required going forward to support the veracity of the data and its translational utility.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
  5. Early Diagnosis and Clinical Significance of Acute Cardiac Injury - Under the Iceberg: A Retrospective Cohort Study of 619 Non-critically Ill Hospitalized COVID-19 Pneumonia Patients

    This article has 10 authors:
    1. Yang Xie
    2. Sichun Chen
    3. Xueli Wang
    4. Baige Li
    5. Tianlu Zhang
    6. Xingwei He
    7. Ningling Sun
    8. Luyan Wang
    9. Hesong Zeng
    10. Yin Shen

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  6. Impact of congestive heart failure and role of cardiac biomarkers in COVID-19 patients: A systematic review and meta-analysis

    This article has 9 authors:
    1. Tarun Dalia
    2. Shubham Lahan
    3. Sagar Ranka
    4. Prakash Acharya
    5. Archana Gautam
    6. Amandeep Goyal
    7. Ioannis Mastoris
    8. Andrew Sauer
    9. Zubair Shah

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  7. Excess of cardiovascular deaths during the COVID-19 pandemic in Brazilian capital cities

    This article has 7 authors:
    1. Luisa Campos Caldeira Brant
    2. Bruno Ramos Nascimento
    3. Renato Azeredo Teixeira
    4. Marcelo Antônio Cartaxo Queiroga Lopes
    5. Deborah Carvalho Malta
    6. Glaucia Maria Moraes Oliveira
    7. Antonio Luiz Pinho Ribeiro

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  8. Chloroquine, but not hydroxychlorquine, prolongs the QT interval in a primary care population

    This article has 6 authors:
    1. Jonas L. Isaksen
    2. Anders G. Holst
    3. Adrian Pietersen
    4. Jonas B. Nielsen
    5. Claus Graff
    6. Jørgen K. Kanters

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  9. Exosomal microRNAs Drive Thrombosis in COVID-19

    This article has 10 authors:
    1. Jessica Gambardella
    2. Celestino Sardu
    3. Marco Bruno Morelli
    4. Vincenzo Messina
    5. Vanessa Castellanos
    6. Raffaele Marfella
    7. Paolo Maggi
    8. Giuseppe Paolisso
    9. Xujun Wang
    10. Gaetano Santulli

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  10. The impact of the COVID-19 pandemic on cardiology services

    This article has 10 authors:
    1. Omar Fersia
    2. Sue Bryant
    3. Rachael Nicholson
    4. Karen McMeeken
    5. Carolyn Brown
    6. Brenda Donaldson
    7. Aaron Jardine
    8. Valerie Grierson
    9. Vanessa Whalen
    10. Alistair Mackay

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity