Allergy and Immunology

  1. Robust spike antibody responses and increased reactogenicity in seropositive individuals after a single dose of SARS-CoV-2 mRNA vaccine

    1. Florian Krammer
    2. Komal Srivastava
    3. the PARIS team
    4. Viviana Simon

    Reviewed by ScreenIT, NCRC

    2 evaluationsAppears in 3 listsLatest version Latest activity

  2. Perinatal granulopoiesis and risk of pediatric asthma

    1. Benjamin A Turturice
    2. Juliana Theorell
    3. Mary Dawn Koenig
    4. Lisa Tussing-Humphreys
    5. Diane R Gold
    6. Augusto A Litonjua
    7. Emily Oken
    8. Sheryl L Rifas-Shiman
    9. David L Perkins
    10. Patricia W Finn

    • Curated by eLife

      Summary: This is a nice study that is clearly written and makes use of several datasets. It attempts to explain perinatal risk factors and the associated risk of developing pediatric asthma in the mid-childhood and early teenage years. Identified among maternal characteristics that were associated with risks of subsequent asthma development included atopy, BMI, race/ethnicity and demographics, birth characteristics, and mode of delivery. The paper then goes on to demonstrate the differences in immune response during the different time frames of pregnancy. Most notably, a gene signature associated with increased myelopoiesis in utero is associated with increased risk of pediatric asthma. Furthermore they show that cord blood serum PGLYRP -1 is associated with reduced risk of pediatric asthma and increased FEV1/FVC. Interestingly sIL6ra which is derived from neutrophils but not associated with neutrophil granules did not show any association with pulmonary outcomes. This suggests that it is the neutrophil granules rather than the neutrophils per se that are the problem association.

    Reviewed by eLife

    3 evaluationsAppears in 1 listLatest version Latest activity

  3. Distinct immune signatures discriminate SARS-CoV-2 vaccine combinations

    1. Nicolás Gonzalo Núñez
    2. Jonas Schmid
    3. Laura Power
    4. Chiara Alberti
    5. Sinduya Krishnarajah
    6. Stefanie Kreutmair
    7. Susanne Unger
    8. Sebastián Blanco
    9. Brenda Konigheim
    10. Constanza Marín
    11. Luisina Onofrio
    12. Jenny Christine Kienzler
    13. Sara da Costa Pereira
    14. Florian Ingelfinger
    15. InmunoCovidCba
    16. InViV working group
    17. Marina E. Pasinovich
    18. Juan M Castelli
    19. Carla Vizzotti
    20. Maximilian Schaefer
    21. Juan Villar-Vesga
    22. Carla Helena Merten
    23. Aakriti Sethi
    24. Tobias Wertheimer
    25. Mirjam Lutz
    26. Danusia Vanoaica
    27. Claudia Sotomayor
    28. Adriana Gruppi
    29. Christian Münz
    30. Diego Cardozo
    31. Gabriela Barbás
    32. Laura Lopez
    33. Paula Carreño
    34. Gonzalo Castro
    35. Elias Raboy
    36. Sandra Gallego
    37. Gabriel Morón
    38. Laura Cervi
    39. Eva V Acosta Rodriguez
    40. Belkys A Maletto
    41. Mariana Maccioni
    42. Burkhard Becher

    Reviewed by Rapid Reviews Infectious Diseases

    2 evaluationsAppears in 1 listLatest version Latest activity

  4. Vitamin D Supplementation Does Not Influence SARS-CoV-2 Vaccine Efficacy or Immunogenicity: Sub-Studies Nested within the CORONAVIT Randomised Controlled Trial

    1. David A. Jolliffe
    2. Giulia Vivaldi
    3. Emma S. Chambers
    4. Weigang Cai
    5. Wenhao Li
    6. Sian E. Faustini
    7. Joseph M. Gibbons
    8. Corinna Pade
    9. Anna K. Coussens
    10. Alex G. Richter
    11. Áine McKnight
    12. Adrian R. Martineau

    Reviewed by Rapid Reviews Infectious Diseases

    4 evaluationsAppears in 1 listLatest version Latest activity
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