Allergy and Immunology

Impaired HA-specific T follicular helper cell and antibody responses to influenza vaccination are linked to inflammation in humans

1. Danika L Hill
2. Carly E Whyte
3. Silvia Innocentin
4. Jia Le Lee
5. James Dooley
6. Jiong Wang
7. Eddie A James
8. James C Lee
9. William W Kwok
10. Martin S Zand
11. Adrian Liston
12. Edward J Carr
13. Michelle A Linterman

• Curated by eLife

  Evaluation Summary:

  This paper will be of significant interest to immunologists interested in understanding the determinants of antibody responses to vaccination. It uses tetramers to specifically identify and track CD4 T cell responses to influenza vaccination in younger and older adults, in an effort to understand why older individuals tend to have lower antibody responses to immunisation. The combination of tetramers, RNA sequencing and TCR clonotype tracking provides a powerful dataset to address fundamental questions of CD4 T cell immunology.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife

Evaluation of Commercial Anti-SARS-CoV-2 Antibody Assays and Comparison of Standardized Titers in Vaccinated Health Care Workers

1. Kahina Saker
2. Vanessa Escuret
3. Virginie Pitiot
4. Amélie Massardier-Pilonchéry
5. Stéphane Paul
6. Bouchra Mokdad
7. Carole Langlois-Jacques
8. Muriel Rabilloud
9. David Goncalves
10. Nicole Fabien
11. Nicolas Guibert
12. Jean-Baptiste Fassier
13. Antonin Bal
14. Sophie Trouillet-Assant
15. Mary-Anne Trabaud

Reviewed by ScreenIT

Comparison of Antibody Levels in Response to SARS-CoV-2 Infection and Vaccination Type in a Midwestern Cohort

1. Laura Remy
2. Chieri Tomomori-Sato
3. Juliana Conkright-Fincham
4. Leanne M. Wiedemann
5. Joan W. Conaway
6. Jay R. Unruh

Reviewed by ScreenIT

Serological survey of SARS-CoV-2 incidence conducted at a rural West Virginia hospital

1. Alexander M. Horspool
2. Brynnan P. Russ
3. M. Allison Wolf
4. Jason Kang
5. Catherine B. Blackwood
6. Jesse M. Hall
7. Ting Y. Wong
8. Megan A. DeJong
9. Graham Bitzer
10. Justin R. Bevere
11. Robert Eggleston
12. Anita Stewart
13. Lisa Costello
14. Shelley Welch
15. Theodore Kieffer
16. Sally Hodder
17. F. Heath Damron

Reviewed by ScreenIT

Development and utilization of a surrogate SARS-CoV-2 viral neutralization assay to assess mRNA vaccine responses

1. Adam V. Wisnewski
2. Jian Liu
3. Carolina Lucas
4. Jon Klein
5. Akiko Iwasaki
6. Linda Cantley
7. Louis Fazen
8. Julian Campillo Luna
9. Martin Slade
10. Carrie A. Redlich

Reviewed by ScreenIT

Antibody attributes that predict the neutralization and effector function of polyclonal responses to SARS-CoV-2

1. Harini Natarajan
2. Shiwei Xu
3. Andrew R. Crowley
4. Savannah E. Butler
5. Joshua A. Weiner
6. Evan M. Bloch
7. Kirsten Littlefield
8. Sarah E. Benner
9. Ruchee Shrestha
10. Olivia Ajayi
11. Wendy Wieland-Alter
12. David Sullivan
13. Shmuel Shoham
14. Thomas C. Quinn
15. Arturo Casadevall
16. Andrew Pekosz
17. Andrew D. Redd
18. Aaron A. R. Tobian
19. Ruth I. Connor
20. Peter F. Wright
21. Margaret E. Ackerman

Reviewed by ScreenIT

An efficient immunoassay for the B cell help function of SARS-CoV-2-specific memory CD4+ T cells

1. Asgar Ansari
2. Shilpa Sachan
3. Bimal Prasad Jit
4. Ashok Sharma
5. Poonam Coshic
6. Alessandro Sette
7. Daniela Weiskopf
8. Nimesh Gupta

Reviewed by ScreenIT

Specialized interferon ligand action in COVID19

1. Matthew D. Galbraith
2. Kohl T. Kinning
3. Kelly D. Sullivan
4. Paula Araya
5. Keith P. Smith
6. Ross E. Granrath
7. Jessica R. Shaw
8. Ryan Baxter
9. Kimberly R. Jordan
10. Seth Russell
11. Monika Dzieciatkowska
12. Julie A. Reisz
13. Fabia Gamboni
14. Francesca Cendali
15. Tusharkanti Ghosh
16. Andrew A. Monte
17. Tellen D. Bennett
18. Kirk C. Hansen
19. Elena W.Y. Hsieh
20. Angelo D’Alessandro
21. Joaquin M. Espinosa

Reviewed by ScreenIT

Immune Responses to a Single Dose of the AZD1222/Covishield Vaccine at 16 Weeks in Individuals in Sri Lanka

1. Chandima Jeewandara
2. Dinuka Guruge
3. Pradeep Darshana Pushpakumara
4. Achala Kamaladasa
5. Inoka Sepali Aberathna
6. Shyrar Tanussiya Ramu
7. Banuri Gunasekera
8. Ayesha Wijesinghe
9. Osanda Dissanayake
10. Heshan Kuruppu
11. Thushali Ranasinghe
12. Deshni Jayathilaka
13. Shashika Dayarathna
14. Dinithi Ekanayake
15. Jeewantha Jayamali
16. Nayanathara Gamalath
17. Anushika Mudunkotiwa
18. Gayasha Somathilake
19. Madhushika Dissanayake
20. Michael Harvie
21. Thashmi Nimasha
22. Deshan Madusanka
23. Tibutius Jayadas
24. Ruwan Wijayamuni
25. Lisa Schimanski
26. Pramila Rijal
27. Tiong K Tan
28. Alain Townsend
29. Graham S Ogg
30. Gathsaurie Neelika Malavige

Reviewed by ScreenIT

Change in Symptoms and Immune Response in People with Post-Acute Sequelae of SARS-Cov-2 Infection ( PASC ) After SARS-Cov-2 Vaccination

1. Daisy Massey
2. Diana Berrent
3. Athena Akrami
4. Gina Assaf
5. Hannah Davis
6. Karen Harris
7. Lisa McCorkell
8. Aaron M Ring
9. Wade L Schulz
10. Hannah Wei
11. Harlan M Krumholz
12. Akiko Iwasaki

Reviewed by ScreenIT