Anti-spike, Anti-nucleocapsid and Neutralizing Antibodies in SARS-CoV-2 Inpatients and Asymptomatic Individuals
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Abstract
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SciScore for 10.1101/2020.05.12.20098236: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: The study was approved by the institutional review board of the Amiens University Medical Center (number PI2020_843_0046, 21 April 2020). Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Neutralization assays were performed by preincubating SARS-CoV-2pp and diluted plasma for 1 h at room temperature before contact with Vero cells (ATCC® CCL-81™) that were transiently transfected with the plasmids pcDNA3.1-hACE2 and pcDNA3.1-TMPRSS2 48 h before inoculation. Verosuggested: ATCC Cat# CCL-81.1, …SciScore for 10.1101/2020.05.12.20098236: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: The study was approved by the institutional review board of the Amiens University Medical Center (number PI2020_843_0046, 21 April 2020). Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Neutralization assays were performed by preincubating SARS-CoV-2pp and diluted plasma for 1 h at room temperature before contact with Vero cells (ATCC® CCL-81™) that were transiently transfected with the plasmids pcDNA3.1-hACE2 and pcDNA3.1-TMPRSS2 48 h before inoculation. Verosuggested: ATCC Cat# CCL-81.1, RRID:CVCL_1K13)Software and Algorithms Sentences Resources Statistical analyses were performed using GraphPad Prism 5. GraphPad Prismsuggested: (GraphPad Prism, RRID:SCR_002798)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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