Herd Immunity against Severe Acute Respiratory Syndrome Coronavirus 2 Infection in 10 Communities, Qatar
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SciScore for 10.1101/2020.09.24.20200543: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Informed consent and questionnaire were provided and collected in nine languages (Arabic, Bengali, English, Hindi, Urdu, Nepali, Sinhala, Tagalog, and Tamil) to cater to the main language groups in these CMW communities.
IRB: The study was approved by HMC and Weill Cornell Medicine-Qatar Institutional Review Boards.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Laboratory methods: Testing for SARS-CoV-2-specific antibodies in the serological samples was performed using an electrochemiluminescence immunoassay, the Roche Elecsys® … SciScore for 10.1101/2020.09.24.20200543: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: Informed consent and questionnaire were provided and collected in nine languages (Arabic, Bengali, English, Hindi, Urdu, Nepali, Sinhala, Tagalog, and Tamil) to cater to the main language groups in these CMW communities.
IRB: The study was approved by HMC and Weill Cornell Medicine-Qatar Institutional Review Boards.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Laboratory methods: Testing for SARS-CoV-2-specific antibodies in the serological samples was performed using an electrochemiluminescence immunoassay, the Roche Elecsys® Anti-SARS-CoV-2 (Roche, Switzerland). Anti-SARS-CoV-2suggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This study has limitations. Testing was conducted in select CMW communities and therefore findings may not be generalizable to the wider CMW population in Qatar. Response rate could not be precisely ascertained given uncertainty around the number of CMWs who were aware of the invitation to participate, but based on employer-reported counts of the size of each community, the response rate is >50% and participants expressed high interest in knowing their antibody status. The validity of study outcomes is contingent on the sensitivity and specificity of the used assays. However, the laboratory methods were based on high-quality commercial platforms, and each diagnostic method was validated in the laboratory before its use. Notably, the antibody assay had high specificity reported at 99.8% [15] by the manufacturer and at 100% by a validation study by Public Health England [27]. In conclusion, at least some of the CMW communities in Qatar, who constitute about 60% of the total population [8], have reached or nearly reached herd immunity for SARS-CoV-2 infection, providing to our knowledge the first empirical evidence for herd immunity worldwide. While achieving herd immunity at a national level is difficult within few months [28], herd immunity could be achieved in specific communities within few months. In such relatively homogenous communities, reaching herd immunity required infection of 65-70% of the members of the community. These findings suggest that the SARS-CoV-2 epidemic...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We found bar graphs of continuous data. We recommend replacing bar graphs with more informative graphics, as many different datasets can lead to the same bar graph. The actual data may suggest different conclusions from the summary statistics. For more information, please see Weissgerber et al (2015).
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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SciScore for 10.1101/2020.09.24.20200543: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Informed consent and questionnaire were provided and collected in nine languages (Arabic, Bengali, English, Hindi, Urdu, Nepali, Sinhala, Tagalog, and Tamil) to cater to the main language groups in these CMW communities. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Laboratory methods Testing for SARS-CoV-2-specific antibodies in the serological samples was performed using an electrochemiluminescence immunoassay, the Roche Elecsys® Anti-SARS-CoV-2 (Roche, Switzerland). Anti-SARS-CoV-2…SciScore for 10.1101/2020.09.24.20200543: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Informed consent and questionnaire were provided and collected in nine languages (Arabic, Bengali, English, Hindi, Urdu, Nepali, Sinhala, Tagalog, and Tamil) to cater to the main language groups in these CMW communities. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Laboratory methods Testing for SARS-CoV-2-specific antibodies in the serological samples was performed using an electrochemiluminescence immunoassay, the Roche Elecsys® Anti-SARS-CoV-2 (Roche, Switzerland). Anti-SARS-CoV-2suggested: NoneResults from OddPub: Thank you for sharing your code.
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
This study has limitations. Testing was conducted in select CMW communities and therefore findings may not be generalizable to the wider CMW population in Qatar. Response rate could not be precisely ascertained given uncertainty around the number of CMWs who were aware of the invitation to participate, but based on employer-reported counts of the size of each community, the response rate is >50% and participants expressed high interest in knowing their antibody status. The validity of study outcomes is contingent on the sensitivity and specificity of the used assays. However, the laboratory methods were based on high-quality commercial platforms, and each diagnostic method was validated in the laboratory before its use. Notably, the antibody assay had high specificity reported at 99.8% [15] by the manufacturer and at 100% by a validation study by Public Health England [27]. In conclusion, at least some of the CMW communities in Qatar, who constitute about 60% of the total population [8], have reached or nearly reached herd immunity for SARS-CoV-2 infection, providing to our knowledge the first empirical evidence for herd immunity worldwide. While achieving herd immunity at a national level is difficult within few months [28], herd immunity could be achieved in specific communities within few months. In such relatively homogenous communities, reaching herd immunity required infection of 65-70% of the members of the community. These findings suggest that the SARS-CoV-2 epidemic...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
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