The Relationship Between COVID-19 Suspected Patient's Coagulation and Platelet Parameters and Polimerase Chain Reaction Results

Aim: Our aim was to investigate the relationship between prothrombintime(PT), activated partial thromboplastin time (aPTT), INR (International Normalized Ratio) and D-dimer levels, platelet (PLT)levels at admission to hospital and positivity or negativity of Polymerase Chain Reaction (PCR) result in patients with suspected COVID-19 followed at COVID-19 services. Material and Method: 238 people who applied with suspicion of COVID-19 in March-April-May of 2020 were included in the study. According to COVID-19 results, PCR negative 119 participants and PCR positive 119 patients were included in the study. PT, aPTT, Ddimer, INR and PLT levels were examined. Results: While PCR negative participants had a mean PT value of 11.46±0.86 sec, PCR positive patients had a mean PT value of 12.97±3.65 sec (p<0.001). There was no significant difference in mean aPTT values of PCR positive and negative patients. Whereas INR, D-dimer increased significantly in PCR positive patients. PLT value decreased from mean value of 266.75±71.36*109/L in PCR negative participants to 241.18±96.64*109/L in PCR positive patients (p=0.002). Conclusion: In our study, it was found that in patients who were admitted to Samsun Training and Research Hospital with COVID-19 suspicion and followed up in COVID-19 services, PT, D-dimer, INR, PLT values were important in detecting Coagulopathy and Thrombocytopenia in the group who were PCR positive according to COVID-19 results. Keywords: COVID-19, PT, aPTT, D-dimer, INR, PLT