Dentists’ Knowledge and Awareness of Antibiotic Prescribing Practices in Damascus, Syria

Inappropriate antibiotic prescribing in dental practice contributes significantly to antimicrobial resistance, yet data on dentists’ prescribing knowledge and behaviors in Damascus, Syria remain limited. This cross-sectional observational study assessed antibiotic-related knowledge and prescribing practices among dentists in Damascus. Conducted between January and March 2024, the study included 844 practicing dentists who completed a validated 48-item electronic questionnaire covering antibiotic indications, dosage, duration, prophylactic use, and management of antibiotic allergies. Knowledge scores (range: 0–48) were categorized as low, moderate, or high. Statistical analysis involved one-way ANOVA with Bonferroni post hoc tests and independent samples t-tests (P < 0.05). Knowledge scores ranged from 10 to 44, with a mean of 28.11 ± 4.61. Low knowledge levels were observed in 46.4% of participants, while 28.6% demonstrated moderate knowledge and 25% high knowledge. Significant differences were found among dental specialties (P < 0.05), with oral and maxillofacial surgeons scoring highest. General dentists were more likely to prescribe antibiotics in inappropriate clinical situations, including chronic periodontitis and localized gingival swelling. No significant associations were found between knowledge scores and years of experience or workplace sector. These findings highlight the need for targeted educational interventions and standardized national guidelines to promote rational antibiotic use in dental practice.