Vancomycin‑Loaded Knee Spacer–Induced Immune Hemolytic Anemia: a case report
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Vancomycin-impregnated polymethylmethacrylate spacers are routinely used in two stage revisions for periprosthetic joint infections. While systemic absorption is considered minimal, rare immune-mediated complications can occur. We report a rare case of immune hemolytic anemia due to a vancomycin-loaded knee spacer, resolved upon its removal.
