Development of a Camel Milk Micro peptide–Gold Nano composite as a Novel Biogenic Anticancer Agent

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Abstract

Background : Cancer persists as a major public health concern worldwide, driving the search for safe and biocompatible therapeutic strategies. Bioactive peptides derived from camel milk, combined with green-synthesized gold nanoparticles, represent a promising approach in anticancer research. Methods: In this study, a novel nanocomposite was developed by conjugating camel milk micropeptides (CMMP) with plant-mediated gold nanoparticles (AuNPs). The resulting camel milk micropeptide–gold nanocomposite (CMMP–AuNC) was physicochemically characterized and evaluated for its in vitro cytotoxic activity against human cancer cell lines. Results: The nanocomposite manifested enhanced anticancer activity compared with individual components, while exerting minimal cytotoxic effects on normal cells, indicating improved cellular targeting. Conclusions: The camel milk micropeptide–gold nanocomposite (CMMP–AuNC) represents a promising biogenic anticancer agent that integrates natural peptide bioactivity with the advantageous properties of gold nanostructures

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