Evaluation of vitamin D and vitamin B12 levels in children with Familial Mediterranean Fever

Introduction: This study aimed to determine the Vitamin D and Vitamin B12 levels in pediatric cases diagnosed with Familial Mediterranean Fever (FMF) and compare these levels with those of healthy controls. Methods This retrospective study included pediatric FMF patients aged 0 to 18 years admitted to a tertiary care hospital and healthy children of similar age and gender. Data were obtained through review of patients' electronic medical records. Results A total of 71 FMF patients were included in the study group and 141 healthy children in the control group. The mean age was 10.5 ± 4.2 years in the study group and 10.2 ± 4.2 years in the control group. There was no significant difference between the groups in terms of age and gender (p > 0.05). When the groups were compared in terms of vitamin D deficiency, the frequency was found to be higher in the study group with a ratio of 57.7% (p = 0.009). There was no significant difference between the groups in terms of vitamin B12 deficiency (p > 0.05). Conclusion This study revealed that vitamin D levels were lower in FMF patients compared to healthy controls, but there was no significant difference in vitamin B12 levels. This finding highlights the importance of screening and monitoring vitamin D levels in FMF patients.