Effectiveness of lifestyle modification intervention program (LMIP) on quality of life among postmenopausal osteoporotic women-A mixed method study

Background Osteoporosis significantly affects the quality of life among postmenopausal women, yet lifestyle-based interventions remain underutilized despite their potential benefits. Objective This study was designed to evaluate the effectiveness of LMIP on the quality of life among postmenopausal women with osteoporosis, along with exploration of barriers and facilitators that influence the undergoing and adoption of the interventions. Methods: A sequential explanatory mixed-methods approach was used for this study. This study was conducted at outpatient department of Kasturba Medical College Hospital, located in Manipal, Karnataka. Phase I was a randomized control trial which was conducted among 120 participants, with 60 each in the experimental and control groups. Quality of life was assessed using the SF-36 quality of life questionnaire. Experimental group participants received LMIP, whereas control group participants received standard care. Those who scored less and higher on the SF-36 questionnaire were the subjects for the in-depth interview in phase II. Results The effectiveness of LMIP on quality of life, analyzed using repeated measures ANOVA, showed significant improvements over time in physical (p = .0003) and mental (p = .000) component scores, making it highly effective for postmenopausal women with osteoporosis. Various barriers and facilitators were identified through the qualitative approach. Conclusion LMIP is an effective, evidence-based approach to improving quality of life in postmenopausal women with osteoporosis. Insights from qualitative findings can inform more tailored and accessible intervention strategies. Registration CTRI/2019/05/019045 (Dated: 10/05/2019)- Registered with the Clinical Trial Registry of India.