The Impact of Risk Factors for Cervical Squamous Cell Carcinoma on Patient Survival Rates at Varying Ratios of Cervical Wall Infiltration Depth

Objective: To investigate whether there are alterations in the influence of various risk factors on the prognosis of patients with cervical squamous cell carcinoma at different infiltration depths. Methods: A retrospective analysis was performed on 644 patients admitted to our hospital between July 2012 and March 2019. Based on postoperative pathological results, the first group (n=322) had cervical wall infiltration approaching nearly 100%, while the second group (n=322) had infiltration below 80%. Results: Univariate analysis revealed that the primary factors affecting patient prognosis in Group 1 were tumor volume(TV), vascular invasion(VI), and lymph node metastasis(LNM) (p<0.01), and maximum tumor diameter(MTD) (p=0.146); Group 2: TV, infiltration depth(ID), and LNM(p<0.05), VI (p=0.097). Multivariate analysis: In Group 1, TV and LNM were independent prognostic factors (p<0.05), whereas Group 2 had no independent prognostic factors. Conclusion: As infiltration depth increases, the impact of TV, LNM, and VI factors on the prognosis of patients with cervical squamous cell carcinoma significantly rises, with TV having a more pronounced effect on prognosis than tumor maximum diameter.