A multidisciplinary approach to establishing clozapine in a patient with schizophrenia and comorbid ASD: A case report

  1. Madelaine Bridges
  2. Agostina Secchi
  3. Eromona Whiskey
  4. Sukhi Shergill
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Abstract

Background: There is substantial symptom overlap in psychosis and autism spectrum disorder (ASD) and co-morbidity is common. In addition, antipsychotic response may be moderated by the co-occurrence. Individuals with ASD may be at greater risk of some clozapine adverse effects and occasionally, its use may be contra-indicated. Case presentation: We present the case of a patient with ASD with psychosis unresponsive to multiple antipsychotics, but extra precaution was required with clozapine Conclusion: A multidisciplinary approach is required to establish clozapine in a patient with schizophrenia and ASD.

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  1. Version published to 10.21203/rs.3.rs-6194533/v1 on Research Square