Bibliometric Analysis of Research on cervical cancer and miRNAs from 2010 to 2024: Research Trends, HotSpots, and Prospects

Background and Purpose MicroRNAs (miRNAs) play multifaceted roles in cervical cancer therapy, including regulating cancer progression, metastasis, drug resistance, HPV control, and metabolic alterations. This study aims to provide a comprehensive bibliometric analysis of the existing literature on miRNAs in cervical cancer, offering insights into research trends, key contributors, and emerging themes to guide future investigations and enhance therapeutic strategies. Method We conducted a systematic search of the Web of Science and PubMed database for literature on miRNAs in cervical cancer published between January 2010 and December 2024. A total of 4034 records were retrieved and analyzed using VOSviewer and CiteSpace software for bibliometric visualization and trend analysis. Results Over the past fifteen years, research on miRNA in cervical cancer showed a significant upward trend before 2020, and then gradually declined starting from 2021. The analysis reveals that Tang and Hua are the most active authors, and China is the most influential country. "Plos One" is the journal that publishes the most articles. Besides, Tianjin Medical University is the most productive institution. The top three high-frequency keywords are "cervical cancer", "expression" and "invasion". Recent keyword and literature analysis indicates that the most notable feature of the current research is the deep integration of basic research and clinical application. Particularly, the cross-integration of non-coding RNA network research with emerging technologies such as nanotechnology and artificial intelligence is promoting the precise diagnosis and treatment system of cervical cancer. These findings highlight the interest in understanding the miRNA-mediated pathways and their clinical significance in cervical cancer. Conclusion This bibliometric analysis provides a comprehensive overview of the research landscape on miRNAs in cervical cancer, identifying key contributors, institutions, and emerging trends. While the study does not predict the future direction of cervical cancer treatment, it offers valuable insights into the current state of research and potential areas for further exploration. The findings underscore the importance of continued investigation into miRNA mechanisms and their therapeutic applications to advance cervical cancer management.