Artificial-Intelligence-Enabled Digital Stethoscope Significantly Improves Point-of-Care Screening for Clinically Significant Valvular Heart Disease

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Abstract

Clinically significant valvular heart disease (VHD) affects 1 in 10 adults over 65 but often goes undiagnosed. In a real-world study of 368 patients, an AI-enabled digital stethoscope demonstrated significantly higher sensitivity than primary care providers (94.1% vs. 41.2%, p=0.002) for detecting audible VHD, albeit with slightly lower specificity. These results suggest that AI-assisted auscultation can enable earlier VHD detection in primary care, improving diagnosis, patient care, and outcomes.

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