Evaluating the Efficacy of Fuzheng Shengjin Decoction in Lung Cancer Treatment: A Clinical Study

Background : Lung cancer is a leading cause of cancer-related death worldwide, with growing interest in complementary and alternative medicine (CAM) approaches to improve patient outcomes. This study aimed to evaluate the safety and efficacy of the traditional Chinese medicine (TCM) formulation, Fuzheng Shengjin Decoction, in lung cancer treatment. Methods : Fifty patients diagnosed with lung cancer received Fuzheng Shengjin Decoction. Primary outcomes included changes in lung function indices, symptom improvement, and quality of life, assessed via validated questionnaires (EORTC QLQ-C30 and QLQ-LC13). Symptom improvements in hemoptysis (42%), sputum production (68%), and cough (75%) were recorded. Lung function showed a mean increase of 0.25 liters in FEV1 and 0.18 liters in FVC. Quality of life improved, with a mean gain of 12.5 points in the EORTC QLQ-C30 Global Health Status and a mean decrease of 15.2 points in the EORTC QLQ-LC13 Lung Cancer Symptom Scale. Results : The decoction was well tolerated, with mild side effects such as diarrhea (16%) and nausea (20%) being the most common. Conclusion : This observational study suggests that Fuzheng Shengjin Decoction may be a promising complementary treatment for lung cancer, potentially improving symptoms, lung function, and quality of life. However, larger randomized controlled trials are necessary to confirm these findings